Switching to new doctor trying decipher old tests

[IceFyre]

So I've recently started the process of enrolling with Defy medical because their telemed program fits my schedule a hell of a lot better than a traditional doctor and at this point all they've done is mess me the hell up.

I was going through my old test results trying to figure out causes and some of my options along with questions to ask when I have the conference over test results from yesterdays vampire visit. I was reviewing my old tests and noticed some things that didn't quite make sense.

Original Diag results for Test:
TESTOSTERONE TOTAL 265 ng/dL
FREE 70 pg/ml
TSH 1.5 uIU/ml
SEX HORMONE BINDING GLOBULIN 18 nmol/L
FSH 4.5 mIU/mL
LH 3.2 mIU/mL
Plus a bunch of other things that don't make a ton of sense at this point fastforward a year and the numbers get stranger.

Current as of last trough draw E5D 100mg test Cyp No AI (This doc didn't run as many pannels)
TESTOSTERONE, TOTAL, LC/MS/MS 690 ng/dL 250-1100
TESTOSTERONE, FREE 221.2 pg/mL 46.0-224.0
TESTOSTERONE,BIOAVAILABLE 464.5 ng/dL 110.0-575.0
SEX HORMONE BINDING GLOBULIN 9 nmol/L 10-50 Below low normal
ESTRADIOL 33 pg/mL
TSH 1.30 mIU/L

I've tried E3D and is what I'm currently at with the results next week and still have not found a happy balance of anything,
constant brain fog, lack of energy, and damn near 0 sex drive. Just trying to figure out what questions I should be asking aside from the basics. I've been reading a shit ton and seen guys with low SHBG not getting a ton out of TRT without low freqent doses.

 

[Systemlord]

When I was doing twice weekly injections SHBG was 16 and when I switched to an every-other-day protocol, SHBG increased to 22.

Low SHBG together with high normal free T usually means high free E2 which can ruin everything. My previous protocol had free T at the top of the range and E2 was always a problem.

I've seen some guys injecting daily doses who were low SHBG which saw an increase vs EOD or twice weekly.

 

[Vince Carter]

He's right the Estrogen is the problem, likely to be the problem that is. Probably the wrong E2 testing, too. Males should only be using the (Ultra) Sensitive LC/MS/MS testing. You as a low SHBG guy should also be using "Estradiol, Free". Defy is aware of this but discuss it specifically at your appointment.