Studies Show No Effect on Cardiovascular Risks from Testosterone

Troutman

New Member
This was a good review of the cardiovascular studies that have come out since the FDA's decision to add warnings on testosterone regarding cardiovascular risk. A good excerpt from the article:

The 5 new studies, along with the many similar studies that preceded them, have convinced many researchers that the balance of evidence, at present, suggests that testosterone replacement therapy is more likely to protect the heart than harm it — and that the FDA’s new warnings are a mistake — but there is even more widespread agreement that only a major randomized trial will settle the matter definitively.

http://www.hcplive.com/medical-news...-health-from-testosterone-replacement-therapy

I do hope the FDA is aware of and keeping track of all the pro-cardiovascular TRT studies that have come out.
 
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This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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