Splitting testosterone into multiple injections

Hammer

Member
Does anyone have lab results or experience in going from one injection of testosterone cypianate per week vs two per week. If you simply cut the prescribed dosage in half will you end up with albiet more stable levels but at a lower percentage of the range? Do you need to go higher that 50% of the original once per week dosage? Feedback is appreciated.
 
No need to go higher than 50% and some guys get a higher average Total T with twice weekly vs. a once a week shot. (with their original dose just cut in half) Typically much less E2 conversion as well as more stable T levels. No more dragging through the last 2-3 days before your weekly injection.
 
Thanks! I'm using approx. .25 mg of Anastrozole 3 times per week. Based on your response I may get away with less. I guess I'll just have to wait for labs and adjust accordingly. I did take Nelson's advice and bought the 27 gauge- 1/2" needles and started should injections..........much easier! Thanks Nelson!
 
Thanks! I'm using approx. .25 mg of Anastrozole 3 times per week. Based on your response I may get away with less. I guess I'll just have to wait for labs and adjust accordingly. I did take Nelson's advice and bought the 27 gauge- 1/2" needles and started should injections..........much easier! Thanks Nelson!

When you adopt a new protocol, be patient. When anything is changed it's important to wait at least four weeks (Dr. Say argues for five, my doctor urges six) and then test. Change one thing at a time so as to avoid too many moving parts. Good luck!
 

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TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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