Same protocol different results

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Hi,

After another 2 months i repeated my blood results on the same protocol 30mg EOD, but now the results are different. I don't know what to make of it.

Total Testosterone: 970 ng/dL |Range: 250 - 865|
Estradiol (we don't have sensitive test in my country): 55.4 |Range: 7.68 - 43|
SHBG: 40 |Range: 13.3 - 89.5|
Free testosterone (TruT): 33.73 ng/dL |Range: 16-31 ng/dL|

Results 2 months ago on the same protocol (i was on that protocol for 50 days, so i was already stable)

Total Testosterone: 1212 ng/dL |Range: 250 - 865|
Estradiol (we don't have sensitive test in my country): 44 |Range: 7.68 - 43|
SHBG: 37 |Range: 13.3 - 89.5|
Free testosterone (TruT): 43.45 ng/dL |Range: 16-31 ng/dL|

Why the results are so different? I've been bulking for 3 months, so i gathered a little bit more body fat than i had during previous blood test, but i don't know if that explains it.

What do you guys think?
I feel pretty much the same, but i just don't know why i have less testosterone and higher estradiol if i didn't change anything and i did blood test at the same hour as previously
 
Defy Medical TRT clinic doctor
I just ran some labs that were curiously very different than expected, I think a few of us are taking lab results with a grain of salt, as they say, as we're seeing just odd results for no known reason, similar to you.
 
I just ran some labs that were curiously very different than expected, I think a few of us are taking lab results with a grain of salt, as they say, as we're seeing just odd results for no known reason, similar to you.

What do you think I should do about that? I mean, i am pretty careful when i am filling my syringe and i am trying to inject always excacly at 11 p.m. Yeah i might one day get 1 extra drop of testosterone and the next time i inject 2 drops less, but cmon, we can't be 100% perfect and i highly doubt that there is a person who gets 100% the exact amount every day forever without some small variations in dosage.
 
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What do you think I should do about that? I mean, i am pretty careful when i am filling my syringe and i am trying to inject always excacly at 11 p.m. Yeah i might one day get 1 extra drop of testosterone and the next time i inject 2 drops less, but cmon, we can't be 100% perfect and i highly doubt that there is a person who gets 100% the exact amount every day forever without some small variations in dosage.
I'm religiously following my stuff right down to having the same lab draw blood in a 30 minute window, I don't variance any part of it and I get some weird numbers that just shakes my faith in it.
 
I'm religiously following my stuff right down to having the same lab draw blood in a 30 minute window, I don't variance any part of it and I get some weird numbers that just shakes my faith in it.

I don't think you shouldn't do anything because you said you feel the same as your previous lab test.

So you guys saying i should just ignore it?
How far off your numbers were from the previous blood test, Vince?
 
absent some negative symptom, yes, leave it alone. I really don't think that just by the numbers that there's a real appreciable difference that as I like to say or think, really changed the landscape of your treatment.
 
absent some negative symptom, yes, leave it alone. I really don't think that just by the numbers that there's a real appreciable difference that as I like to say or think, really changed the landscape of your treatment.

Thanks, by the way, do you that 1mg difference between injections are a huge deal on EOD protocol? Like i said, i am really trying to get as close to exacly 30mg as i can, but i honestly think i am not 100% perfect about it, so a little varation is possible. Could that be a reason for such a change?
 
I doubt it and I don't know that you can get THAT precise such that you could replicate it, over time.

Yeah, I think you're right. Huge difference like 5mg - sure, no one is going to make that mistake when they're careful, but a very small difference like 1-2 drops of testosterone more (or less) is pretty common i think. ALSO, i've noticted that the size of a marker on my syringes are different from each other. The model is the same and everything, but I see it all the time. One time the marker is bigger, one time its smaller. So yeah, a little varation is very possible just because of that.
 
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madman

Super Moderator
Hi,

After another 2 months i repeated my blood results on the same protocol 30mg EOD, but now the results are different. I don't know what to make of it.

Total Testosterone: 970 ng/dL |Range: 250 - 865|
Estradiol (we don't have sensitive test in my country): 55.4 |Range: 7.68 - 43|
SHBG: 40 |Range: 13.3 - 89.5|
Free testosterone (TruT): 33.73 ng/dL |Range: 16-31 ng/dL|

Results 2 months ago on the same protocol (i was on that protocol for 50 days, so i was already stable)

Total Testosterone: 1212 ng/dL |Range: 250 - 865|
Estradiol (we don't have sensitive test in my country): 44 |Range: 7.68 - 43|
SHBG: 37 |Range: 13.3 - 89.5|
Free testosterone (TruT): 43.45 ng/dL |Range: 16-31 ng/dL|

Why the results are so different? I've been bulking for 3 months, so i gathered a little bit more body fat than i had during previous blood test, but i don't know if that explains it.

What do you guys think?
I feel pretty much the same, but i just don't know why i have less testosterone and higher estradiol if i didn't change anything and i did blood test at the same hour as previously
Hi,

After another 2 months i repeated my blood results on the same protocol 30mg EOD, but now the results are different. I don't know what to make of it.

Total Testosterone: 970 ng/dL |Range: 250 - 865|
Estradiol (we don't have sensitive test in my country): 55.4 |Range: 7.68 - 43|
SHBG: 40 |Range: 13.3 - 89.5|
Free testosterone (TruT): 33.73 ng/dL |Range: 16-31 ng/dL|

Results 2 months ago on the same protocol (i was on that protocol for 50 days, so i was already stable)

Total Testosterone: 1212 ng/dL |Range: 250 - 865|
Estradiol (we don't have sensitive test in my country): 44 |Range: 7.68 - 43|
SHBG: 37 |Range: 13.3 - 89.5|
Free testosterone (TruT): 43.45 ng/dL |Range: 16-31 ng/dL|

Why the results are so different? I've been bulking for 3 months, so i gathered a little bit more body fat than i had during previous blood test, but i don't know if that explains it.

What do you guys think?
I feel pretty much the same, but i just don't know why i have less testosterone and higher estradiol if i didn't change anything and i did blood test at the same hour as previously




It could very well be variance in numbers from the testing methods as even when using the same labs/testing assay.....discrepancy can happen.

As VC states:
"I'm religiously following my stuff right down to having the same lab draw blood in a 30 minute window, I don't variance any part of it and I get some weird numbers that just shakes my faith in it"


You stated....."Why the results are so different? I've been bulking for 3 months, so i gathered a little bit more body fat than i had during previous blood test, but i don't know if that explains it"

Depending on what a little truly means as we have no way of knowing exactly how much body fat you have added to your frame in the past 3 months during your bulk and believe it or not excess adipose can definitely cause your T to drop some while at the same time increasing e2.

There will be a ramp up in aromatization of T----->e2 as adipose is increased whether through excess caloric intake or simply too much inactivity.
 

madman

Super Moderator
Yeah, I think you're right. Huge difference like 5mg - sure, no one is going to make that mistake when they're careful, but a very small difference like 1-2 drops of testosterone more (or less) is pretty common i think. ALSO, i've noticted that the size of a marker on my syringes are different from each other. The model is the same and everything, but I see it all the time. One time the marker is bigger, one time its smaller. So yeah, a little varation is very possible just because of that.


Highly doubtful injecting 5 extra mg T weekly is going to cause your TT to be 200+ ng/dL higher than your previous labs!
 
It could very well be variance in numbers from the testing methods as even when using the same labs/testing assay.....discrepancy can happen.

As VC states:
"I'm religiously following my stuff right down to having the same lab draw blood in a 30 minute window, I don't variance any part of it and I get some weird numbers that just shakes my faith in it"


You stated....."Why the results are so different? I've been bulking for 3 months, so i gathered a little bit more body fat than i had during previous blood test, but i don't know if that explains it"

Depending on what a little truly means as we have no way of knowing exactly how much body fat you have added to your frame in the past 3 months during your bulk and believe it or not excess adipose can definitely cause your T to drop some while at the same time increasing e2.

There will be a ramp up in aromatization of T----->e2 as adipose is increased whether through excess caloric intake or simply too much inactivity.

Thank you. Yeah, i am begging my cut this week, because i feel like i got too fat.

Highly doubtful injecting 5 extra mg T weekly is going to cause your TT to be 200+ ng/dL higher than your previous labs!

So, there is no way that is caused by a little variations in dosage when injecting? It wouldn't throw me out of whack? Like i was during a protocol change before i reached 6 weeks?
 
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CaptianCurious

New Member
Those results don't seem too surprising to me.

I'll try and find a study I found that dealt with this issue. It placed the individual variation in Total T as +/- 150 ng/dl measurements on the same day each week. I think it was 100 mg/weekly in 1 shot but in 3 weeks your results could be 500,800, 620, or so, on day 5 (or whatever day). So over a range of 300 ng/dl on the same 100 mg/wk dose.

It doesn't seem too surprising really - if you add up all the ng/dl in the 5 liters of blood you have, it adds up to less than a mg, and daily production's 3 mg - 10 mg in 90% of people, so the blood levels don't tell the whole story.

I went looking for the story after I already suspected it. Personally, I don't really believe the "we're all different" adage that goes around the boards, in the broad sense that it's used. I think there's this variation, different people test different days, and many have other issues that aren't T related. Very few natural males make >100 mg/wk Test Cyp equivalent, so for T related issues, that should set most anyone straight, imo. If that doesn't make someone feel better than the emphasis should shift to other systems or subsystems.

Personally, I wouldn't worry about it if the dose is reasonable and your other biological markers are okay.
 
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