SAMe Improves Fatigue, Depression, and Protects the Liver

Have u had any blood work checked to see if that fish oil is working? Cholesterol or any other type of blood work that fish oil may actually change? Hdl, ldl etc…?
Blood work yes but nothing in the results that could be attributed to taking or the cessation of taking fish oil. Just too many other variables.
 
Took the foil wrapped tablets at 400mg a day but didn’t notice any positive effects that I could identify, so stopped about 6 weeks ago with still no discernible difference.

Also decided to stop the Omega 3. Been taking 6g to 10g a day for the past couple of years but whenever I temporarily stop like when being on holiday I notice no difference so thinking g about stopping for a longer duration to see if I notice anything.
The research I have seen used SAM-e, 1600mg divided into two doses, morning evening for 8 weeks. I don't think you took enough for depression.
 
The research I have seen used SAM-e, 1600mg divided into two doses, morning evening for 8 weeks. I don't think you took enough for depression.
It wasn’t taken for depression but if 1600mg is the suggested dosage for other reasons then it becomes pretty expensive.
 

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Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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