Recent "Total Testosterone" + "Free Testosterone" Blood Work For 46 Year Old Male?

burnoutat42

Member
Hello All

I'm hoping some of you far more knowledgeable than myself can possibly help me out? I recently started TRT again in late October 2022 after a 2.5 year hiatus. My recent blood work states that my "Total Testosterone" is over 1500 and my "Free Testosterone" is 30.1 while my "Estradiol" is 60.2?

I'm currently on a TRT protocol of 200mg of Test Cypionate taken 2X week or 100ml split into two shots / doses. Before going back on TRT my "Total Testosterone" was 172 while my "Free Testosterone" was 5.2? Something just seems off based on past test results which I would be more than happy to share.

I have previously never exceeded "1000 Plus Total Testosterone" and my free has never previously exceeded 25? Additionally my "Estradiol" is usually around the 29-30 range? I'm including my test results below...thanks in advance for any help / suggestions.
 

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You have a more urgent problem than your testosterone level.

Discusss ASAP with your doctor: low hemoglobin (anemia or bleeding somewhere ?), high platelets, high neutrophils (infection?).

Do a COVID test.

Reduce the dose to 50mg Testosterone, twice weekly (total 100mg/week). It is strange that your Hematocrit % is not elevated at such high testosterone.
 
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Thanks for your reply as it's greatly appreciated. My "Hemoglobin" test results back in mid October 2022 were also "Low" at 12.7. They were additionally "Low" at 12.5 back in September of 2018.
 
Do a COVID test to rule it out first.

It could be an infection, anemia, or cancer. Go to a primary doctor and a hematologist. This is not something to ignore for years. Your hemoglobin and hematocrit are not responding to a massive dose of testosterone, which is suspicious because testosterone stimulates those.
 
I'm currently on a TRT protocol of 200mg of Test Cypionate taken 2X week or 100ml split into two shots / doses.
This is a mild steroid cycle for most men and is too much for TRT dosages.

The endocrine society recommends 75-100 mg weekly.

As for the low hemoglobin and MCV, welcome to the iron deficiency club.

It’s possible your iron could recover once you bring down your TT and FT levels to a normal level and if not, iron supplementation may be needed.
 
Everything has been off ever since going through "Klonopin / Benzo" WD over five years ago! I additionally came off numerous other RX drugs and I'm now 110% RX / Drug free. To the best of my knowledge I can remember this was an issue in years past.
 
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This is a mild steroid cycle for most men and is too much for TRT dosages.

The endocrine society recommends 75-100 mg weekly.

As for the low hemoglobin and MCV, welcome to the iron deficiency club.

It’s possible your iron could recover once you bring down your TT and FT levels to a normal level and if not, iron supplementation may be needed.
I understand what your saying and will keep that in mind "Thanks".
 
This is a mild steroid cycle for most men and is too much for TRT dosages.

The endocrine society recommends 75-100 mg weekly.

As for the low hemoglobin and MCV, welcome to the iron deficiency club.

It’s possible your iron could recover once you bring down your TT and FT levels to a normal level and if not, iron supplementation may be needed.
My "Iron Levels" were roughly in the same range three months ago prior to resuming TRT Therapy. My "Total T was 172" and "Free T was 5.2" and my "Hemoglobin" levels were 12.7. Perhaps I need to look into various ways I could potentially increase my "Iron Levels"...thank you for giving me some insight here as it's greatly appreciated.
 
Everything has been off ever since going through "Klonopin / Benzo" WD over five years ago! I additionally came off numerous other RX drugs and I'm now 110% RX / Drug free. To the best of my knowledge I can remember this was an issue in years past.
How long did it take you to heal from the benzos? Those drugs are the reason I don’t touch pills of any kind anymore.
 
I wouldn't say I'm "100% Healed" as I still continue to struggle with intermittent "WAVES" on occasion. Never in my wildest dream did I think at now four years post all RX Drugs that I would still be struggling.
 

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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