Questions about my Low LH and FSH.

[Jman]

Hello guys,
Im hoping to get a little informa on how to manage Low LH and FSH. Im a 52 year old male whose been on testosterone cyponate for 4 years. Secondary Hypogandis.
My levels are good, except estradiol is a ***** getting it in the sweet spot. 20-30
I take anastarole to control the estradiol and also HCG every 3 days. 5,000
Im fixed, take B12, C and Zinc daily but those level are low.
So my questions are these. Should I be concerned? what can I do to increase these levels and how Would these low levels effect me.
Any suggestions?

 

[madman]

Hello guys,
Im hoping to get a little informa on how to manage Low LH and FSH. Im a 52 year old male whose been on testosterone cyponate for 4 years. Secondary Hypogandis.
My levels are good, except estradiol is a ***** getting it in the sweet spot. 20-30
I take anastarole to control the estradiol and also HCG every 3 days. 5,000
Im fixed, take B12, C and Zinc daily but those level are low.
So my questions are these. Should I be concerned? what can I do to increase these levels and how Would these low levels effect me.
Any suggestions?

No need to test LH/FSH as the HPG axis will be shut down on trt.

*Sperm production depends on a functionally intact HPG axis with the normal pituitary secretion of LH and FSH to support testicular testosterone production and spermatogenesis. Exogenous testosterone suppresses the HPG axis and testicular testosterone production

The Effect of Longer-Acting vs Shorter-Acting TRT on FSH and LH - Excel Male TRT Forum

Abstract Introduction: Testosterone (T) replacement therapy causes suppression of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) that can lead to a decrease in semen parameters and possible infertility. Different T formulations may have varying suppression on FSH and LH...

www.excelmale.com

Short-acting T therapy to maintain homeostasis that more closely reflects normal physiology - Excel Male TRT Forum

Short-Acting Testosterone: Physiologic? Gerwin Westfield, Ursula B Kaiser, Dolores J Lamb, Ranjith Ramasamy INTRODUCTION Pulsatile secretion of a hormone refers to the intermittent secretion of the hormone in a burst like or episodic manner rather than constantly, with the frequency...

www.excelmale.com

What is your protocol (dose T/injection frequency) and were labs done at true trough?

Your TT 635 ng/dL is far from high let alone we have no idea where your FT level truly sits as you had it tested using an inaccurate assay.....the piss poor direct immunoassay.

The only way to know where your FT level truly sits is to have it tested using the most accurate assays such as the gold standard Equilibrium Dialysis or Ultrafiltration (next best).

Your RBCs/hemoglobin/hematocrit are all on the high end.

There is no magic so-called sweet spot (20-30) for estradiol.....comes down to the individual and where they feel best!

That is a whopping dose of hCG you are using!

Top it off that you never included your SHBG as not only will it have a significant impact on TT/FT but can dictate what injection frequency may suit you best.

 

[Systemlord]

Wow that's a lot of HCG, most you should inject at any one time is 500 iu. This crazy high HCG dose is the reason for your high E2.

 

[Dicky]

Wow that's a lot of HCG, most you should inject at any one time is 500 iu. This crazy high HCG dose is the reason for your high E2.

Amen to that

 

[Nelson Vergel]

Men on TRT live with zero LH and FSH for years. Only now we are starting to get limited data on zero LH's lowering effect on upstream neurosteroids like pregnenolone and progesterone. These two are associated with mood and calmness.