PT-141 Appears to work great only when sleeping?!

[Lonestar71]

Godd morning!

PT-141 works amazing when I'm sleeping but not when attempting to actually plan a night with my wife. I've taken it in the morning, late afternoon and couple of hours before the deed. Zero affects until I go to sleep which turns into a raging erection that won't relax until I get up and walk around. It maintains a "chub" throughout the following day.

Any input / suggestions would be greatly appreacited!

THanks!

 

[Systemlord]

Maybe there is a hormone imbalance during waking hours that does exists when sleeping.

 

[Lonestar71]

I am currently on TRT / HCG.

 

[Systemlord]

I am currently on TRT / HCG.

HCG can cause sexual issues and can create an imbalance of many different hormones.

 

[Guided_by_Voices]

Nor-epinephrine decreases during sleep which IIRC has a pro-erectile affect. I and many others have found that PT-141 seems to require sleep to fully "activate" it. Away from sleep, I have found PT-141 to enhance the affect of the viagra-like compounds, but not to be miraculous on on its own. IME it is one variable but not the only variable.

 

[Cataceous]

C

Thread 'A different dosing strategy with bremelanotide (PT-141) yields dramatically better results'

Sep 28, 2023

Could microdosing PT-141 (bremelanotide) deliver better libido results than standard doses? Many men find that typical PT-141 doses (500mcg-2mg) produce disappointing or inconsistent effects on libido—but a different dosing strategy involving multiple small daily doses may unlock dramatically better results by better mimicking natural α-MSH physiology.

This detailed discussion documents a protocol using 15-20mcg of bremelanotide injected 5 times throughout the day, which produced high sustained libido and easy erections—far superior to single large doses. We discuss the science...

• Cataceous
• bremelanotide microdosing pt-141
• Replies: 70
• Forum: When TRT Is Not Enough (ED, Libido, & More)

• 

 

[Lonestar71]

Thanks for the info! So, should I scehdule a powernap prior to activity? LOL

Is there a workaround?

The results are amazing when my kickstand wakes me up @ 2:00AM!

 

[Systemlord]

Testosterone can increase norepinephrine released from kidneys. So if you’re overdosed on TRT/hCG or you choose a half-life where hormones are consistently elevated, having less fluctuations, are sensitive to hormones in general, this can have an effect of overstimulation and therefore affect norepinephrine levels.

I found I have better erectile function and libido with my ferritin and on the lower end. Once my ferritin gets above 100, things start going downhill. So taking anything that boosts iron absorption while on TRT may prevent your body from regulating iron balance, hemoglobin and hematocrit.

 

[Lonestar71]

Thank you again, I'm attempting to comprehend your advice. lol

Does a full blood panel show ferritin levels? Is this a good inidicator of overdosing?

I just want my libido back.

 

[Systemlord]

Does a full blood panel show ferritin levels?

A ferritin blood test shows ferritin levels.

I just want my libido back.

It’s well known that hCG can negatively affect libido.

 

[excelnelg]

Isn't it understood that the effects of PT-141 are totally unpredictable?

 

[tomu]

Godd morning!

PT-141 works amazing when I'm sleeping but not when attempting to actually plan a night with my wife. I've taken it in the morning, late afternoon and couple of hours before the deed. Zero affects until I go to sleep which turns into a raging erection that won't relax until I get up and walk around. It maintains a "chub" throughout the following day.

Any input / suggestions would be greatly appreacited!

THanks!

Hi and good morning...Yes, thats seems to happen for a lot of us, It takes hours for me....However, It starts working after a few, but then when I go to sleep....I also can't because of outrageous erections... I mean very large, very, very hard,,, If I have sex then,,, It's back as soon as I try to sleep....So, it's this cycle of sleep, a little wake-up, and then a very hard time trying to sleep again. I would not mind this, but it doesn't keep my wife awake, so it's just me. My hard dick and a long night,,,, The next day I am still horny but feel likecrapfrom not getting good sleep...I am 74 and in good health and have no ED. I even thought if this erection does not calm down, will I need to go to the ER,, I did not need to, but I love being that horny, love the erections, but hate not sleeping....BTW, I have guardianship of my grandkids, so there is no rest the next day...What a dilemma!!