Prostate Cancer Diagnosis From Evolution to Revolution

madman

Super Moderator


In this comprehensive interview, host Dr. Geo chats with guest expert Dr. Samir Taneja from NYU Langone Medical Center. They unpack the shift in prostate cancer diagnostics from traditional methodologies to more effective approaches using MRI and ultrasound technology. They also touch on the possibility of focal therapy becoming a more standard course of treatment. Dr. Taneja shares his clinical experience and insight on various studies and trials, making this podcast a must-listen for anyone interested in the latest developments in prostate cancer research and treatment.




Chapters

00:00 Prostate Cancer Diagnosis: From Evolution to Revolution with Samir Taneja, MD
00:58 Evolution of Prostate Cancer Diagnosis
04:49 Prostate Cancer Diagnosis
06:23 The Impact of PSA Screening
08:28 MRI in Prostate Cancer Diagnosis
10:06 Controversy and Criticism of PSA Screening
15:41 Role of MRI Fusion in Prostate Cancer Diagnosis
22:07 The Future of Prostate Cancer Diagnosis
32:30 Understanding MRI Interpretation and Biopsy Challenges
33:33 The Impact of Patient's State on Biopsy Accuracy
34:06 Anesthetizing the Prostate and Biopsy Methods
34:25 Transrectal vs Transperoneal Biopsies
40:14 The Importance of Radiologists in MRI Interpretation
43:01 The Potential of Micro Ultrasound in Prostate Biopsies
48:56 The Future of Focal Therapy in Prostate Cancer Treatment
49:30 The Role of MRI in Active Surveillance
53:31 The Vapor Two Trial and the Future of Focal Therapy
 
 

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TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

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Normal range: 300-1000 ng/dL

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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