MRI Secrets for Prostate Cancer

madman

Super Moderator

In this video, a urologist discusses the use of MRI in the diagnosis and treatment of prostate cancer. MRIs are used to direct treatment decisions, assess the extent of cancer, and detect recurrences. The urologist explains how the MRI process works, the different imaging sequences used, and the role of contrast in identifying tumors. They also discuss the importance of biopsies in determining tumor grade and treatment options. The video highlights the benefits of MRI in sparing men from unnecessary biopsies and enabling targeted focal therapy. The urologist emphasizes the significance of MRI in determining tumor location, proximity to critical structures, and planning treatment margins.


Key Takeaways:

*MRIs are used in the pathway of prostate cancer diagnosis and treatment.

*MRIs are helpful in guiding treatment decisions for men with relapsed cancer or those on surveillance.

*MRI provides a more comprehensive and detailed image of the prostate compared to biopsies.

*In the UK, MRI is recommended before biopsy for men suitable for radical treatment.

*Contrast-enhanced MRI helps detect tumors and monitor treatment response.

*MRI scans typically last around 40 minutes and can be challenging for claustrophobic individuals.

*Multi-parametric MRI includes T2-weighted and diffusion-weighted images to identify cancerous area

*Dynamic contrast imaging shows how quickly tumors take up and lose contrast.

*Radiologists provide a confidence score to assess the likelihood of cancer based on MRI findings


*MRI allows for targeted focal therapy by identifying tumor location and proximity to critical structures.
 
 
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TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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