Primary Hypogonadism?

BBaller

New Member
Hey guys,

Just ordered Nelson's book and have been reading through it, and just noticed the section on primary hypogonadism. Basically- it's when your testes just don't produce more T. The signal is there, LH and FSH tend to be high, but circulating T levels don't increase.

Anyway- here's my relevant blood work for as long as I've been testing, with lab notations:

July 2014
T- 327 LOW
Free T- 76.8
(LH/FSH not tested)

Nov 2014
T- 566
LH- 12.5 HIGH
FSH- 18 HIGH
(Free T not tested)

April 2015
T- 288 LOW
LH- 6.5
FSH- 21.2 HIGH
(Free T not tested)

Sept 15 2015
T- 337 LOW
LH- 9.4 HIGH
FSH- 19.5 HIGH

Sept 30 2015
T- 395
Free T (Direct)- 13
(LH/FSH not tested)

My question is: does this matter in terms of considering treatment? Is primary vs secondary more subject to lifestyle adjustments?
 
Dear Vince- apologies on the delayed reply.

Thank you for sharing those links. I did look through them and read a bit more about primary vs secondary hypogonadism.

Based on what I understand in my situation, my body is already doing as much as it can to produce more T, but the output from the testes just isn't there. It's obviously a bummer, but in some ways almost more satisfying that it may be an organic issue rather than something I'm doing poorly, or failing to do.

Anyway, thanks again.
 

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Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

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Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

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The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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