Post-Finasteride Syndrome

madman

Super Moderator


Endocrinologist Professor Michael Irwig shares his experiences seeing patients with persistent side effects from finasteride, a drug marketed to young men for male pattern baldness.

Post-Finasteride Syndrome is the current term for a rare syndrome of devastating physical, neurological, and sexual side effects that persist and progress after stopping finasteride. The condition occurs primarily in younger men who have taken the drug to treat hair loss. There is currently no effective treatment for this disease.

PFS has a disastrous impact on patients, their families, and their friends. It often causes disability, isolation, and suicide. Every person is valuable, and everyone deserves to make a fully informed choice with their health.

More research into Post-Finasteride Syndrome is desperately needed. Learn more about and support important new scientific research here:
https://pfsnetwork.org/donate
 

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hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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