microbeast
New Member
Hello everyone. I'm 40 years old I've been on trt for a little over 4 years. Unfortunately I've never been able to consistently dial in my TRT protocol. I've suffered high and low estrogen symptoms this whole time but especially this last year year and a half mostly low estrogen. When this happens I get very bad anxiety and blood pressure spikes all the way up in the 200s. If my estrogen becomes high BP can go through the roof but typically it only last hours as I treat it with Anastrozole. However because there's no consistent Anastrozole dose that works for me I often blow past my sweet spot and end up with low estrogen that can last several days. Both ways my blood pressure can be over 150/90+. I've tried everything. Subq, micro dosing testosterone, micro dosing Anastrozole as low as .0625 or 1/16th a mg. I've kept a journal tracking what I'm taking how often and how I feel. I've tried different doses. The only thing i haven't tried and am currently trying is ultra low doses. I am a hyper responder. Off 120mg my trough is 1344ng/dl. Anyhow i was always worried I was doing some kind of permanent damage and I'm devastated I may have reached that point. I've lost errection strength, sensitivity, orgasm intensity and even desire. I don't know what's worse that I may never have a decent sex life or that I possibly shortened my life span maybe even significantly. I've done a lot of reading and the data points to a very high percentage of sexual dysfunction is vascular related especially in the presence of high blood pressure. I wish this was some kind of anxiety and or depression but frankly I'm only depressed because of this situation and im only anxious when estrogen is out of balance. I really don't know what to do here. I'd like to quit but I just had cervical spine surgery ACDF and no testosterone would or could dramatically hinder my recovery. I'm hoping anyone here could give me any advice, feedback or a solution. I'm also curious if anyone has suffered the same consequences as myself and hope to prevent this happening to anyone else. I am a very knowledgeable guy. I have spent months researching how to reduce estrogen or how to dial in TRT with no avail. I will say I can at times still get it up but everything is about 70% as it was just 3 months ago. The ironic thing is when my hormones are in the sweet spot my BP is 110/70. I just can't believe this is happening. How often I have these bp spikes and high and low estrogen varies to once a week or less to a whole week of low estrogen. Hopefully I can get some help or advice. Please help me guys I'm so very disappointed in myself and especially frustrated with the lack of management from Defy Medical. All they ever did was asked what can I get cha. Never did they say hey your testosterone is off the charts, how's your blood pressure, how do you feel? Thanks in advance for anyone who takes the time to help or share in any way. I hope no one has to go through this. I literally feel like I'm living in a nightmare.
On a positive note. I have had an echo that came back mostly normal except mild LVH. I was doing avid cardio before my surgery and had a resting heart rate of 50 bpm. I also had multiple test done by a company called life line. They used ultrasound to check for peripheral artery disease, carotid artery disease, arterial fibrillation and abdominal aortic aneurysm and all came back completely normal. In addition I still get nocturnal errections. Which I suppose I a good sign. If sexual function was absolutely horrible I would imagine it wouldn't be happening. I just want to stress this isn't psychological nor is it medication related. I've been on TRT for awhile and while sexual health can suffer if estrogen is high or low there's always been periods where my sexual function was ridiculously good. This has not occurred in about 8 weeks give or take a week. Now it also seemed to happen pretty quickly. It wasn't a slow decline. Just 8 or so weeks ago I had my original raging sexual function. Well hopefully someone has some good info. I'm also curious if maybe you guys think there's a different type of testosterone delivery method which will not cause as many fluctuations like a gel or patch. Please advise.
On a positive note. I have had an echo that came back mostly normal except mild LVH. I was doing avid cardio before my surgery and had a resting heart rate of 50 bpm. I also had multiple test done by a company called life line. They used ultrasound to check for peripheral artery disease, carotid artery disease, arterial fibrillation and abdominal aortic aneurysm and all came back completely normal. In addition I still get nocturnal errections. Which I suppose I a good sign. If sexual function was absolutely horrible I would imagine it wouldn't be happening. I just want to stress this isn't psychological nor is it medication related. I've been on TRT for awhile and while sexual health can suffer if estrogen is high or low there's always been periods where my sexual function was ridiculously good. This has not occurred in about 8 weeks give or take a week. Now it also seemed to happen pretty quickly. It wasn't a slow decline. Just 8 or so weeks ago I had my original raging sexual function. Well hopefully someone has some good info. I'm also curious if maybe you guys think there's a different type of testosterone delivery method which will not cause as many fluctuations like a gel or patch. Please advise.
