PCOS: A challenging condition with both reproductive and metabolic components

madman

Super Moderator

Dr. Kathleen Hoeger discusses PCOS, a challenging condition with both reproductive and metabolic components. Diagnosis involves evaluating menstrual cycling, androgenic symptoms, and the appearance of the ovaries on ultrasound. Treatment varies depending on the individual’s needs and may include addressing insulin resistance. PCOS awareness can be raised through events like PCOS Awareness Month and international guidelines. Dr. Hoeger is part of the ASRM Androgen Excess Special Interest Group, which offers postgraduate courses and support for early career professionals interested in PCOS.


Key Takeaways:


*PCOS is a complex condition with reproductive and metabolic implications.

*Diagnosis is based on evaluating menstrual cycling, androgenic symptoms, and ovarian appearance on ultrasound.

*Treatment for PCOS varies depending on individual needs.

*Addressing insulin resistance is an important aspect of PCOS treatment.

*PCOS awareness can be raised through events like PCOS Awareness Month and international guidelines.

*Dr. Kathleen Hoeger is part of the ASRM Androgen Excess Special Interest Group.

*The Group offers postgraduate courses and mentorship for early career professionals interested in PCOS.

*PCOS is linked to an increased risk of diabetes and cardiovascular disease.

*Proper diagnosis is key to addressing the concerns of patients with PCOS.


*ASRM and other organizations are working to promote awareness and provide resources for PCOS.
 

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Predict estradiol, DHT, and free testosterone levels based on total testosterone

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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