PAUL-E
Member
Palmitoylethanolamide (PEA), an endogenous fatty acid amide, has been demonstrated to bind to a receptor in the cell nucleus – the peroxisome proliferator–activated receptor – and performs a great variety of biological functions related to chronic and neuropathic pain and inflammation, as has been demonstrated in clinical trials. These include peripheral neuropathies such as diabetic neuropathy, chemotherapy-induced peripheral neuropathy, carpal tunnel syndrome, sciatic pain, osteoarthritis, low-back pain, failed back surgery syndrome, dental pains, neuropathic pain in stroke and multiple sclerosis, chronic pelvic pain, postherpetic neuralgia, and vaginal pains. Probably due to the fact that PEA is an endogenous modulator as well as a compound in food, such as eggs and milk, no serious side effects have been reported, nor have drug–drug interactions. This article presents a case series describing the application and potential efficacy and safety of PEA in the treatment of various syndromes associated with chronic pain that is poorly responsive to standard therapies.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500919/
I came across this and thought it could help some and it was interesting since its a naturally occurring substance in the body it is virtually side effect free(in the right doses).
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500919/
I came across this and thought it could help some and it was interesting since its a naturally occurring substance in the body it is virtually side effect free(in the right doses).
Last edited by a moderator:
