New to TRT: 8 days into generic Testim use (Advice/help)?

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Xerxes

New Member
For the last year have been experiencing anxiety, minor depression, ED issues, lowered libido, etc. Had some ED issues in college as well, but has it under control for last 7-8 years or so. I am 35 and married with 2 kids.

First went to doc for anxiety and ED issues in June of 2014. He did blood work. Everything was good except for B-12 and T-levels (250.88). I started taking B-12 at his suggestions and starting working out and losing weight. I am now in best shape of my life. At worst point (3 years ago) I was 212 lbs at 5'8'..Now I am 162 lb.

In October 2014 went to urologist b/c was still having ED and anxiety issues. He did blood work and my numbers were up slightly to 279.9 (probably from some weight loss and lifestyle changes). He gave me a trial of 5 mg cialis for daily use. My wife was freaked out by the cialis, so I didn't use it. Had previously been fine with the ED stuff for a very long time, so I don't think it is mechanical anyway.
After antidepressants, anxiety meds, much weight loss, etc., I decided to go back to urologist to check T levels again (with wife's blessing). Numbers up again to 281.9 on 5/4/15, but still low for my age(or at all!). Se we decided to try TRT.

I just started T-gel a little over a week ago. The script was for Testim, but the pharmacy gave me the new generic brand (which annoyingly cost more than the preferred Testim, but that is not a real issue at this point). I use one 5 mg tube in the am each day, and this is my 8th day.

At the start (first 3 days), I felt pretty good. Energy way up, some morning wood, a few spontaneous erections, feeling pumped about the prospect of getting better..

For the last 4 days, I've felt pretty bad: lower energy, no morning wood at all, no spontaneous erections, a much lower libido, and most distressingly a very much increased anxiety level.

For the last year or so I have been battling anxiety, but it had been reasonably in check. A few days after starting the gel it has roared back (So much so that i have had to use my xanax to manage it).

So basically instead of the desired effects, the gel has resulted in the opposite: more anxiety, less erection quality and frequency, and a very low libido (lower than before starting).

I did some research online (I know, always a bad idea), and some guys on TRT suggest taking DIM (it's an estrogen blocker supplement). I took one last night to see if that was the problem. (I know that sometimes the T can convert to E2 in some men, which would lead to the negative symptoms I was experiencing). This morning I woke up in a worse place emotionally.

Some other sources seemed to indicate the exogenous T can shut down the body's own natural production as well.

So, I am writing to ask a few questions of any seasoned veterans of TRT and/or medical professionals (I also emailed these to my urologist as well):

1- if this is normal (i.e. this will pass and then my levels will start going up and I'll feel good and I should just stay the course and stick it out)?

2- should I be taking the DIM estrogen blocker or is it unnecessary (or even a negative addition)?

3- should we try to increase/decrease my dose? Some people seem to have better success on 2 tubes a day

4. -is the downward symptomatic trend just my body shutting down its own production and we need to wait for the exogenous T to build up and elevate my levels and all will be well in the near future?

5. -are shots a better option (particularly cypionate)? most people see them as much more effective than the transdermals.

Right now I have an appointment to see my doctor next on June 4th for a check up/blood draw/numbers check in reevaluation of method and dosing of treatment.

I appreciate any an all advice/suggestions/encouragement..

Thanks!
 
Defy Medical TRT clinic doctor
1- if this is normal (i.e. this will pass and then my levels will start going up and I'll feel good and I should just stay the course and stick it out)?

2- should I be taking the DIM estrogen blocker or is it unnecessary (or even a negative addition)?

3- should we try to increase/decrease my dose? Some people seem to have better success on 2 tubes a day

4. -is the downward symptomatic trend just my body shutting down its own production and we need to wait for the exogenous T to build up and elevate my levels and all will be well in the near future?

5. -are shots a better option (particularly cypionate)? most people see them as much more effective than the transdermals.

Right now I have an appointment to see my doctor next on June 4th for a check up/blood draw/numbers check in reevaluation of method and dosing of treatment.

I appreciate any an all advice/suggestions/encouragement..

Thanks!


I am sorry that you are still experiencing issues even after starting Testim.

1- Testim is not the best gel. It only has 1 percent testosterone, it smells, and may not bring guy's testosterone to levels above 600 ng/dL. Some guys' TT ends up being lower than what they started with (dose is too low in those cases). You could be one of them (you will know in your follow up visit tests). You may want to spend under $60 per month on a 2 percent compounded gel or injectable testosterone instead. You can choose also to test your own testosterone and estradiol ( I have a site in which I made that affordable: www.DiscountedLabs.com )

Hey, why did your wife "freak out" when you wanted to start daily Cialis? It seems like a red flag to me that something is not right.

2 and 3- I would not make any changes without lab test results (TT, FT, E2 by sensitive method, free T3, CBC and CMP as minimum)

4- Answered in 1.

5- Some people do great on gels and some don't. Shots tend to probably make guys feel better since blood levels tend to be higher in general (depends on the dose).

Please let us know if you have any questions. You are not alone. There are over 5000 guys here that can help.
 
Hi Xerxes -

I'm one of those for whom gels (Androgel) did not do a whole lot as Nelson mentioned. My levels never got high enough - I think I was around an overall of 400-500 at best. Just did not feel all that great.

I went to shots and within a few months I felt immeasurably better. I've been on shots now for 9 months (100 mg / week broken into 2 injections every 3.t days) and feeling good consistently. Consistent overall T (800/900 range), no estradiol issues, consistent morning erections, and I'm far more consistently mentally and emotionally balanced on a daily basis with little ups and downs.
 
Beyond Testosterone Book by Nelson Vergel
I was on Androgel and Testim and I felt worse after using them. I was prescribed Tes. Cypionate 200mg/2 weeks and it was good. I felt alot better. I was taken of and put on testopel because my urologist isn't a fan of injections. Testopel has led me to anxiety and depression.
 
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