Need advice on first lab results, my initial Defy consultation is 5 weeks away

Guys, since 11/24 I've been on the 14mg daily injection schedule, on 11/30 received and started the Calcium D-glucarate 500mg twice daily and DIM 200mg daily. Also been taking 50mg Zinc daily and some days 100mg.

The last 3-4 days have been strange, bad insomnia, night sweats, hot flushing in my face and feeling a lot of stress to the point of my eyes starting to tear up for no good reason a few times. Would you think it's ok to bump up the Calcium D-glucarate and DIM. Appointment with Dr. Saya is two weeks from Tuesday. This high E2 is really awful, I'm going to ask him about raloxifene for the gyno I'm pretty certain I have. Have been doing a lot of cardio (bike) and sweating and a healthy diet and my belly/chest fat has increased this week.

I posted an estradiol level of 55, which for me was uncomfortable (though not the level of discomfort you are dealing with). I dealt with night-sweats, off and on, for two weeks and a lot of sensitive, itching nipples. Things slid into place as I kept injecting 16mg of testosterone every day. It took a month before my serum levels had adjusted - as my doctor had warned me it might. Is the same thing going on with you? I can't say with certainty since I'm not a doctor, I can only offer my own experience, and point out that your new protocol is not yet two weeks old. I'm sorry you're dealing with this.
 
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This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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