Has anyone tried navel transdermal testosterone application? This study Navel absorption: transdermal bioavailability of testosterone shows bioavailability of 79.9% compared to 49.9% forearm administration.
Yes, I've tried scrotal testosterone dissolved in 10% DMSO and worked very well but caused testicular pain so I had to stop.I’m sure the concentration of nearby veins in that area helps. Are you familiar with applying a transdermal T (cream) to the scrotum? I don’t have the paper in from of me, but it states a near 8x increase in testosterone bioavailability for absorption in scrotum application vs abdominal application.
Predict estradiol, DHT, and free testosterone levels based on total testosterone
This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.
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A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.
Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.
The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.
Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.
DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038