My wife starting T Cream

Hello all,
My wife is 50 years old. Never had kids and is in menopause. She has low T, no energy, brain fog, hot flashes. So she did pellets. Worked ok for 2 out of 12 weeks she had them in. (Week 6 and 7 ONLY). The rest of the time showed no results. Been off T pellets for 4 months. She was taking estrogen or progestrone pills. She thinks they were acting like birth control and making her gain weight and doing nothing). She's been off those for 2 months.

So this week they changed and put her on cream 4 clicks per day 3MG/G. Taking Unisome at night for sleep. Taking no other meds.

1. She wants to know the best time of day to apply the cream. She wakes up around 8am, works out at 4pm and showers at 5pm. She is concerned if she applies the cream after she showers, she is going to get bump in energy at night when she is sleeping. (Typically after showering is said to be best for absorption because hot water soaks open the pores in the skin) When she really needs the energy is during the morning and daytime. Please advise.

2. Where is the best locations to apply it? I assume she needs to rotate sites.
 

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This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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