More Muscle Mass: Lower Risk of Diabetes in Older Women

Nelson Vergel

Founder, ExcelMale.com
Greater muscle area is associated with lower risk of diabetes in older women with normal weight, but not in men or overweight women, according to a study involving more than 2,100 older adults.

Participants were diabetes-free at baseline. Investigators measured abdominal and thigh muscle area, as well as total body lean mass. They assessed strength via grip and knee extensions. Among the results:

• There were 265 (12.2%) cases of diabetes after a median 11.3 years of follow-up.

• There was no link between muscle or strength measures and diabetes in adjusted models.

• Normal weight women with greater muscle mass were less likely to have diabetes.

• Greater muscle predicted lower diabetes risk in normal weight women, and greater risk in overweight and obese women.

• There were no significant interactions by BMI category for strength measures or any measures for men.


Citation: Larsen B, Wassel C, Kritchevsky S, et al. Association of muscle mass, area, and strength with incident diabetes in older adults: The Health ABC Study. [Published online ahead of print March 1, 2016]. J Clin Endocrinol Metab. doi:http://dx.doi.org/10.1210/jc.2015-3643.
 

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Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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