Metformin side effects

Good morning! does you doctor have you on Met to treat type two diabetes? I tried it for a a month to see if I would benefit from it but just did not feel well on it. I just eat a lower carb diet and am just fine now with a 5.1 A1C
Do you actually have type 2 diabetes or are you insulin resistant?
 
I do not. Was really intrigued by all the positive talk about it. I had noticed anytime I tried to eat any candy my blood sugar would stay elevated for hours. I decided it was just not worth is to have any sweets. My body fat runs 15% and as long as get my exercise in and eat clean my glucose stays around 75-85. my fasting insulin was just tested at 7.8 and my ND wants it 7 or under. do you know anything on those ranges? Labcorp says up to like 21?? seems kind of high to me.
 
Metformin and exercise independently improve insulin sensitivity and decrease the risk of diabetes. Metformin was also recently proposed as a potential therapy to slow aging. However, recent evidence indicates that adding metformin to exercise antagonizes the exercise‐induced improvement in insulin sensitivity and cardiorespiratory fitness.

Metformin inhibits mitochondrial adaptations to aerobic exercise training in older adults.
 
I do not. Was really intrigued by all the positive talk about it. I had noticed anytime I tried to eat any candy my blood sugar would stay elevated for hours. I decided it was just not worth is to have any sweets. My body fat runs 15% and as long as get my exercise in and eat clean my glucose stays around 75-85. my fasting insulin was just tested at 7.8 and my ND wants it 7 or under. do you know anything on those ranges? Labcorp says up to like 21?? seems kind of high to me.
Sounds like you're doing an excellent job controlling your iinsulin levels. I also follow a low-carb diet, for the same reason you are. To control my insulin levels.
 
Is Metformin a good first-line treatment for newly diagnosed or pre-diabetics? My uncle was recently diagnosed type 2 diabetes and the doc went straight to insulin medications.
 
Is Metformin a good first-line treatment for newly diagnosed or pre-diabetics? My uncle was recently diagnosed type 2 diabetes and the doc went straight to insulin medications.
Varies with the patient (and the doctor). Low-carb diet and exercise is a good initial approach, to be followed with metformin if blood sugar goals aren't reached. But many doctors will place a patient who presents with persistent significantly elevated blood sugars (e.g., fasting state of over 160 mg/dl) on insulin immediately.
 
Varies with the patient (and the doctor). Low-carb diet and exercise is a good initial approach, to be followed with metformin if blood sugar goals aren't reached. But many doctors will place a patient who presents with persistent significantly elevated blood sugars (e.g., fasting state of over 160 mg/dl) on insulin immediately.
Fasting glucose of 160 would be pretty scary.
 
One of Defy's PAs noticed that my A1c was creeping up and had reached the point of pre-diabetes (type-2). She told me to try a supplement called Berberine. Comes in 250 mg capsules and doses just like Metformin. Added plus is that it doesn't have any of the gastric side effects of Metformin.

Adding insult to injury, I also have Hashimotos (have to take both T4 and T3 meds). One of Defy's PAs suggested that I go on a gluten and dairy free diet. So between that and a significant reduction in sugar intake, I've managed to bring my fasting glucose below 90 and my A1c to a very comfortable 4.8 to 5.0. Added bonus is that the gluten/dairy free diet has reduced my thyroid antibodies by 50% (they're still elevated though). It's helped me.
 
One of Defy's PAs noticed that my A1c was creeping up and had reached the point of pre-diabetes (type-2). She told me to try a supplement called Berberine. Comes in 250 mg capsules and doses just like Metformin. Added plus is that it doesn't have any of the gastric side effects of Metformin.

Adding insult to injury, I also have Hashimotos (have to take both T4 and T3 meds). One of Defy's PAs suggested that I go on a gluten and dairy free diet. So between that and a significant reduction in sugar intake, I've managed to bring my fasting glucose below 90 and my A1c to a very comfortable 4.8 to 5.0. Added bonus is that the gluten/dairy free diet has reduced my thyroid antibodies by 50% (they're still elevated though). It's helped me.
Would Defy treat diabetes?
 
I suppose they would. I do know they treat thyroid, so why not diabetes too? The Defy portal (where I order my Rx meds) includes ordering Metformin. Have not seen insulin there though.
 
One of Defy's PAs noticed that my A1c was creeping up and had reached the point of pre-diabetes (type-2). She told me to try a supplement called Berberine. Comes in 250 mg capsules and doses just like Metformin. Added plus is that it doesn't have any of the gastric side effects of Metformin.

Adding insult to injury, I also have Hashimotos (have to take both T4 and T3 meds). One of Defy's PAs suggested that I go on a gluten and dairy free diet. So between that and a significant reduction in sugar intake, I've managed to bring my fasting glucose below 90 and my A1c to a very comfortable 4.8 to 5.0. Added bonus is that the gluten/dairy free diet has reduced my thyroid antibodies by 50% (they're still elevated though). It's helped me.
You can also buy metformin through Reliable RX
 

hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

Beyond Testosterone Podcast

Online statistics

Members online
3
Guests online
185
Total visitors
188

Latest posts

Back
Top