Men with a Family History of Prostate Cancer (PC) Who Get on TRT Do Not Develop PC More than Others.

Nelson Vergel

Founder, ExcelMale.com

The main findings of the study on prostate cancer risk in men with testosterone deficiency (TD) and a family history of prostate cancer (PCa) receiving testosterone therapy (TTh) are:

- **Prostate Cancer Risk:** There was no significant difference in the 10-year risk of PCa diagnosis between men receiving TTh (6.26%) and those not receiving TTh (5.46%) (HR 0.81, 95% CI 0.51 to 1.28).
- **Active Treatment for PCa:** The risk of requiring active treatment for PCa was also not significantly different between the TTh group (2.73%) and the non-TTh group (3.69%) (HR 0.55, 95% CI 0.29 to 1.03).
- **Conclusion:** Testosterone therapy did not increase the risk of PCa diagnosis or treatment in this population, offering reassurance about its safety in men with TD and a family history of PCa. Further research is recommended to confirm these findings.

Sources
[1] From Data to Discovery: The Findings Section of a Research Paper From Data to Discovery: The Findings Section of a Research Paper
[2] How to write the findings of a research paper? | MW Editing How to write the findings of a research paper?
[3] How to Write the Results/Findings Section in Research - Wordvice How to Write the Results/Findings Section in Research - Wordvice
[4] what is are the findings or results of the study research ? - Brainly.ph https://brainly.ph/question/8339973
[5] How to Write the Results/Findings Section in Research Papers How to Write the Findings Section in Research Papers
[6] Research Findings Guide: Examples, Types, and Structuring Tips Research Findings Guide: Examples, Types, and Structuring Tips
[7] 1. What are the findings of the research? 2. What - Brainly.ph https://brainly.ph/question/11258872
[8] [PDF] Results/Findings Sections for Empirical Research Papers https://www.jmu.edu/uwc/_files/link-library/empirical/findings-results_section_overview.pdf
 

Re-evaluating testosterone therapy: new insights for men with familial prostate cancer risk​



 

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⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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