Marius Pharmaceuticals Partners with US Specialists Management

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RALEIGH, N.C., Jan. 14, 2025 (GLOBE NEWSWIRE) -- Marius Pharmaceuticals, a pharmaceutical company focused on developing innovative therapies for testosterone deficiency, has partnered with USSM, an independent physician owned/controlled Management Services Organization (“MSO”) through their Urologic in-office pharmacies and dispensaries. USSM practices include Urology Partners of North Texas, Urology of St. Louis, Urology of Iowa, Arkansas Urology, and Tennessee Valley Urology. This USSM distribution model is for KYZATREX® (testosterone undecanoate) CIII capsules, an FDA approved, cash only oral prescription drug that is used to treat adult men who have low or no testosterone levels due to certain medical conditions.

“The KYZATREX distribution model is unique because we circumvent large retail pharmacy chains and are a cash-only RX, allowing urologic practices nationwide to eliminate insurance burdens, commonly associated with testosterone,” said Polly Sawyer, Senior VP of Commercial Development at Marius.

In today’s healthcare landscape, with rampant insurance company burdens, such as prior authorizations, USSM upholds the business model of in-office dispensing, while simultaneously facilitating patient convenience and compliance.


“With USSM’s progressive ancillary focus, our goal is to maintain independence and create opportunities for our physician partners without sacrificing cash flow, administrative control, and patient care,” said Bob Yonke, CEO of USSM. “Our in-house pharmacies have been a significant component within our continued business growth.”
 
 
 
 

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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