Low Energy / Low Libido / Poor Sleep / High Cortisol / Low (Free) T (?)

@StepbyStep I know this is an old thread, but how did the T3 treatment go?

I also have high RT3 (26 on a range of 9-24), and high cortisol is most likely the problem as iron and ferritin are at good levels.
I tried T3 at 25mcg's per day up to 50mcg's per day with no improvement in symptoms.
 
@StepbyStep I know this is an old thread, but how did the T3 treatment go?

I also have high RT3 (26 on a range of 9-24), and high cortisol is most likely the problem as iron and ferritin are at good levels.
I tried T3 at 25mcg's per day up to 50mcg's per day with no improvement in symptoms.
It has been a while since I went through the T3 treatment. My life and TRT protocol was a mess during that time and I felt awful. The only thing I do know is that the T3 treatment was successful in lowering my RT3 as well as my TSH. (TSH was 2.5ish prior and went down to 1).

I got my life sorted out, started using iodized salt when cooking and eat a brazil nut once in a while and got my TRT protocol sorted out. My TSH has been holding steady at 1.5ish since(first bloods of 2022 getting done today though). Whether the T3 treatment helped I do not know.

I suspected high Cortisol too and did a couple diurnal tests. No abnormalities found.
 

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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