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lunke

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Trying to figure this out. Background, Started TRT about a year ago after noticing I had all the signs of low t and getting tested at 270 at 48 years of age.

The clinic I was using injected TRT and HCG. Normalized my Test level at about 800 for the first couple months after a large spike on a once-weekly dose of 100 where the trough was at 1500. Reduced to once weekly at 75. T measured 800ish, Estradiol ultimately spiked to well above 50.

They then recommended an AI, overprescribed the dosage and crashed my estradiol level to less than 5, that was horrible. Switched clinics went from shots to pellets on a quarterly basis no HCG.

Have been doing this for 6 months. The last check-in a month ago test was 1100, free t 26, estradiol 24. In theory, this seems pretty darn good.

However, my desire for sex has basically disappeared. When I first started T had morning wood and a stiff breeze got me wanting to have sex again. Physically everything is working when it's time to have sex. Mentally though I am struggling with desire and sex drive. I do drink regularly and no drugs.

I'm in very good shape physically, 195lbs, 14% body fat, workout 5 times a week, a relatively low-stress job as a consultant who works from home. When I started T my mood was fantastic most days, now it's closer to what it was when I had low T.

Ordered the 4 step cortisol test today. I take tadalafil daily 5mg.

I have been a lurker on this board for a while and really could use some of your thoughts. Thank you in advance.
 
Last edited:
Defy Medical TRT clinic doctor
When my TT was at 1100 and e2 at 20, my doc told me that my estradiol was too low compared to my high T level. We backed off the AI and now I feel great with e2 at 77 and TT 1385 at last check. My libido was hit or miss before, now it’s pretty much always on my mind.

Not sure what high e2 sides you were dealing with when it was 50, but if you can tough it out, after 2-3 weeks, it’s better on the other side. My 2 cents
 
Pellets are a very poor choice, allows no titration dose over the life of the pellets and they can be, its not unheard of to also contain Anastrozole/Armidex...can you verify that?

But basically too little info, we pride ourselves on seeing lab tests, are the correct tests being used, etc etc With it there's little of an substantive conversation that can be had to what's going on with you.
If you have a set of lab tests with these pellets let's see what you have.
 
Thanks swoops36 that is helpful. I stopped taking the AI about a week ago. Most of the high e2 symptoms originally could have been just because i was too dialed into what could happen.

Vince, thats a great question and I don't know. I'll dig into it on Monday.
 
The levels may not be the problem, but having the levels fluctuating during the week may be a problem. Some men don't respond well to TRT injecting infrequently.

You will get limited info doing limited labs, there could be thyroid problems, mineral deficiencies, cortisol imbalance which would see TRT not work very well.

It took me 2 years to figure out my dosing schedule on injectable cypionate and it doesn't seem like you tinkered with dosing much at all.
 
However, my desire for sex has basically disappeared. When I first started T had morning wood and a stiff breeze got me wanting to have sex again. Physically everything is working when it's time to have sex. Mentally though I am struggling with desire and sex drive. I do drink regularly and no drugs.

Are you married, dating, etc? When you watch porn, do you get stimulated? When you masturbate, do you get fully hard and orgasm normally? It's not all about the numbers on your lab report.
 
Trying to figure this out. Background, Started TRT about a year ago after noticing I had all the signs of low t and getting tested at 270 at 48 years of age.

The clinic I was using injected TRT and HCG. Normalized my Test level at about 800 for the first couple months after a large spike on a once-weekly dose of 100 where the trough was at 1500. Reduced to once weekly at 75. T measured 800ish, Estradiol ultimately spiked to well above 50.

They then recommended an AI, overprescribed the dosage and crashed my estradiol level to less than 5, that was horrible. Switched clinics went from shots to pellets on a quarterly basis no HCG.

Have been doing this for 6 months. The last check-in a month ago test was 1100, free t 26, estradiol 24. In theory, this seems pretty darn good.

However, my desire for sex has basically disappeared. When I first started T had morning wood and a stiff breeze got me wanting to have sex again. Physically everything is working when it's time to have sex. Mentally though I am struggling with desire and sex drive. I do drink regularly and no drugs.

I'm in very good shape physically, 195lbs, 14% body fat, workout 5 times a week, a relatively low-stress job as a consultant who works from home. When I started T my mood was fantastic most days, now it's closer to what it was when I had low T.

Ordered the 4 step cortisol test today. I take tadalafil daily 5mg.

I have been a lurker on this board for a while and really could use some of your thoughts. Thank you in advance.


Have a complete thyroid test done before going further. Great info here:
Trying to figure this out. Background, Started TRT about a year ago after noticing I had all the signs of low t and getting tested at 270 at 48 years of age.

The clinic I was using injected TRT and HCG. Normalized my Test level at about 800 for the first couple months after a large spike on a once-weekly dose of 100 where the trough was at 1500. Reduced to once weekly at 75. T measured 800ish, Estradiol ultimately spiked to well above 50.

They then recommended an AI, overprescribed the dosage and crashed my estradiol level to less than 5, that was horrible. Switched clinics went from shots to pellets on a quarterly basis no HCG.

Have been doing this for 6 months. The last check-in a month ago test was 1100, free t 26, estradiol 24. In theory, this seems pretty darn good.

However, my desire for sex has basically disappeared. When I first started T had morning wood and a stiff breeze got me wanting to have sex again. Physically everything is working when it's time to have sex. Mentally though I am struggling with desire and sex drive. I do drink regularly and no drugs.

I'm in very good shape physically, 195lbs, 14% body fat, workout 5 times a week, a relatively low-stress job as a consultant who works from home. When I started T my mood was fantastic most days, now it's closer to what it was when I had low T.

Ordered the 4 step cortisol test today. I take tadalafil daily 5mg.

I have been a lurker on this board for a while and really could use some of your thoughts. Thank you in advance.


Thyroid Symptoms in Men + How Low Thyroid Causes Low Testosterone
You might want to have a detailed Thyroid test done. Great info here.
 
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