Long-term Testosterone Beneficial in Hypogonadal Men

Jinzang

Member
There is a good summary of the health benefits of TRT on Medscape Medical News. Results are from an 8 year follow up of patients on TRT.

For hypogonadal men, long-term treatment with an injectable form of testosterone improves sexual and urinary function, and, in hyopogonadal men with type 2 diabetes, it also improves glycemic control, registry data out to 8 years indicate.

In addition, it leads to striking changes in body composition, including reductions in waist circumference, body mass index (BMI), and body weight, and increases in lean muscle mass.
"Testosterone is one of the most beneficial — and at the same time, the most underestimated and under-rated — treatment modalities for hypogonadal men," said Farid Saad, MD, honorary professor at Gulf Medical University in Ajman, United Arab Emirates, and therapeutic area head of global medical affairs andrology at Bayer AG in Berlin.
"It's just amazing what it does, and it certainly does not deserve the bad reputation it has," he told Medscape Medical News.
"We need to do our best to convince healthcare professionals and the authorities that testosterone is actually a very beneficial treatment that confers many health benefits on these men, including less cardiovascular disease and fewer cardiovascular events," he explained.
Dr Saad presented his team's findings at the Sexual Medicine Society of North America Fall 2016 Scientific Meeting in Scottsdale, Arizona.
 
In the study does it say the age of the men, I wonder what happens when a man is in eighties or nineties and is on TRT? I hope we find out.
 

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This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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