Localized Prosate Cancer Patients Should Receive TRT Following Treatment

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CoastWatcher

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A urologist at Queen's University, Kingston, Ontario, Canada, argues in a recent edition of "European Focus: Urology," "that a hypogonadal man with successfully treated localized prostate cancer deserves testosterone therapy (TTh/TRT) regardless of grade. The evidence is not conclusive but compelling. The story is different for those with intermediate-risk disease who, for a variety of reasons, need TTh/TRT but cannot or elect not to have treatment of their primary malignancy, but still desire androgen supplementation."

The situation for a man who finds he is dealing with intermediate risk prostate cancer is somewhat more complex. However, even men in that situation should be evaluated according to the criteria in the table presented below to determine if TRT is appropriate.

  • Competent, qualified, and interested treating physician

  • Patient able and willing to provide informed consent

  • Clinical picture compatible with diagnosis of significant testosterone deficiency

  • Serum testosterone levels supporting the diagnosis of testosterone deficiency

  • Gleason grade group <2&#8211;3

  • Disease confined to the pelvis (stage <T2c)

  • Absence of contraindications (erythrocytosis, sleep apnea, congestive heart failure)

http://www.eu-focus.europeanurology.com/article/S2405-4569(17)30161-X/fulltext

This yet another voice calling for doctors and surgeons to reconsider the long-standing aversion many have toward testosterone therapy for prostate cancer patients. The belief that TRT is absolutely contraindicated can no longer be supported.

 
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