Liver Values (AST/ALT) missing from new bloodwork

[Johnny Swole]

Hey guys, question for anybody that has had bloodwork done through discount labs before and after the transition from Labcorp to Quest. I ordered the same test that I always get. TRT Male Hormone/Wellness Followup Panel and can't find the AST and ALT results anywhere. They were high last time and I was trying to get them down and wanted to see how successful I was. I checked the site again and they are still included in the package.

Any idea why they may have not been tested or included on the PDF?

Thanks!!!

 

[Nelson Vergel]

We are processing your request now at DiscountedLabs.com

 

[Johnny Swole]

Thank you, sir! Love the PDF from Quest so much more than the one from Labcorp

 

[Nelson Vergel]

Yes, a lot more colorful and easy to see ranges.

 

[Johnny Swole]

Looks like CMP wasn’t included on my lab requisition

 

[Johnny Swole]

Thank you so much for correcting this for me and making it right. Much appreciated, Nelson

 

[Johnny Swole]

Nelson, would you be able to answer a few question for me?

1. Is there a difference between Estrodial Sensitive and Estrodial Ultra Sensitive? Mine was 45 on both of my tests this year. The Labcorp range is 8.0-35.0 and the Quest range is < OR = 29 pg/mL.

2. On the free Test, the Labcorp range is 6.8-21.5 and mine in January was 27.2. On the Quest test last week my result was 334.6 and the range is 35.0-155.0 pg/mL

3. My SBG went from 8 to 24. What are some things that affect that? And is higher better?

Thank you!!!!

 

[Nelson Vergel]

1. Is there a difference between Estradiol Sensitive and Estradiol Ultra Sensitive? Mine was 45 on both of my tests this year. The Labcorp range is 8.0-35.0 and the Quest range is < OR = 29 pg/mL.

There are the same test. Quest chose to call theirs ultrasensitive. Lab ranges mean nothing for estradiol except for the lowest value which we know from studies should not be low (approx 15 pg/ml) due to bone loss.

For men with testosterone under 675 ng/dL (NHANES cohort), these were median estradiol levels (measured by ECLIA, not sensitive test).

Source: Age-Specific Serum Total and Free Estradiol Concentrations in Healthy Men in US Nationally Representative Samples

If we assume that sensitive E2 may be lower than regular by 20% in healthy men, then assume a max median E2 by LC/MS of 30 mg/mL for TT under 700 ng/dl.

This study also shows the predicted (ECLIA) estradiol for different T doses:

How to Predict Estradiol and DHT at Different Testosterone Doses

I was able to come up with a table using the predictive model equation derived from data in this study: The Effects of Injected Testosterone Dose and Age on the Conversion of Testosterone to Estradiol and Dihydrotestosterone in Young and Older Men Summary This video discusses a research paper...

www.excelmale.com

2. On the free Test, the Labcorp range is 6.8-21.5 and mine in January was 27.2. On the Quest test last week my result was 334.6 and the range is 35.0-155.0 pg/mL

Free Testosterone is about 2% of total. LabCorp and Quest ranges are derived from all men in their US database (men with low T , normal T and High T). Just multiply your total T by 0.20 to get to what your expected free T is.

I tend to agree more with Quest on this one. I had sent several emails to Labcorp to complain about their low and narrow range but they never addressed it.


3. My SBG went from 8 to 24. What are some things that affect that? And is higher better?

You probably lowered your T dose. SHBG level means nothing to me when free T is 2 %or above. Lean healthy men and women have higher SHBG. People with insulin resistance have low SHBG. Higher T doses decrease SHBG.

 

[Johnny Swole]

3. My SBG went from 8 to 24. What are some things that affect that? And is higher better?

You probably lowered your T dose. SHBG level means nothing to me when free T is 2 %or above. Lean healthy men and women have higher SHBG. People with insulin resistance have low SHBG. Higher T doses decrease SHBG.

This makes total sense. Around the time of the first test I was on "extra" and had come off recently.

 

[Johnny Swole]

2. On the free Test, the Labcorp range is 6.8-21.5 and mine in January was 27.2. On the Quest test last week my result was 334.6 and the range is 35.0-155.0 pg/mL

Free Testosterone is about 2% of total. LabCorp and Quest ranges are derived from all men in their US database (men with low T , normal T and High T). Just multiply your total T by 0.20 to get to what your expected free T is.

I tend to agree more with Quest on this one. I had sent several emails to Labcorp to complain about their low and narrow range but they never addressed it.

I assume you meant multiply by .02, not .20
In that case my free test should be around 21, but it's over 300. That sounds way off, no?

 

[Nelson Vergel]

I assume you meant multiply by .02, not .20
In that case my free test should be around 21, but it's over 300. That sounds way off, no?

By 0.2 since you want pg/mL not ng/dL.

 

[Johnny Swole]

By 0.2 since you want pg/mL not ng/dL.

Ohhhhhh. I saw 2% and assumed.
Ok, so by those computations my free test would be 239 at 20%. Mine is 335. something to be concerned about?

 

[Nelson Vergel]

Ohhhhhh. I saw 2% and assumed.
Ok, so by those computations my free test would be 239 at 20%. Mine is 335. something to be concerned about?

Nah. Count your blessings

 

[Johnny Swole]

Nah. Count your blessings

Thank you, Nelson. Always appreciate your feedback. I do feel like I'm in a sweet spot right now, especially libido wise