Lab measurement unit wrong? FT/TT = 0.14%* possible?

Wise_S

New Member
My total testosterone is 886 ng/dl (900 is the top of the ref range), shbg = 67.67 nmol/l ( 18,30-54,10), albumin = 5.3 g/dL;

I also tested my free testosterone and the lab result was 12.0 ng/l (8,30-40,10). If I convert it to ng/dl, that will be 1.2 ng/dl. This means that my FT/TT = 0.14% even though both TT & FT are in the normal range. Is this possible?

I talked to the lab and they asked their doctor to check if there is a mistake with the measurement unit and he said everything is ok. I'm not sure though...

I suspect that my FT should be 12.0 ng/dl (not ng/l). Then my FT/TT will be 1.4%, which is much more realistic. Also when I use this calculator:

www issam.ch/ freetesto.htm

and plug in my numbers, my FT is calculated as being 11.6 ng/dL = 1.31 %, which is much closer to 12 ng/dl, than to 12 ng/l. Bioavailable T = 332 ng/dL = 37.5 %.

Any thoughts on this issue?
 
Your doctors are wrong, I might add that there is still a large gap in knowledge for what constitutes an androgen deficiency and no two doctors can agree. Your Free T is 11.6 ng/dL = 1.31 % when Total T and SHBG are calculated and 2-3 percent is considered normal and higher albumin is worsening the situation. Even this has its problems as it's just a calculation, Free T measurements are still largely unreliable, Total T labs is far more accurate.

We know SHBG binds up our testosterone and when we present with high SHBG you can bet free T will be low regardless of any lab test especially when the patient is presenting with the common symptoms of an androgen deficiency. Doctors need to go back to their roots, treat the patients symptoms and not the labs.

If you're presenting with the common symptoms of an androgen deficiency it's not hard to understand why, your doctor is the problem here. I believe FeelingLost is onto to something here, sometimes doctors don't want to stick their neck out for the patient.
 
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Yeah I have a similar issue. My lab numbers: 297 ng/dL total and 8.3 pg/mL free... if you convert to get the same units so they cancel out, that puts my free/total testosterone as measured by LabCorp at 0.28%

But if I use that link to do a calculation based on albumin, SHBG and total testosterone, it says I should have a free testosterone of 1.86%.

I'm confused by it. But what it seems like guys here are saying is that the direct measurement of free T is highly variable and therefore kind of unreliable...? So why should we even test for it? I don't know.
 
Yeah I have a similar issue. My lab numbers: 297 ng/dL total and 8.3 pg/mL free... if you convert to get the same units so they cancel out, that puts my free/total testosterone as measured by LabCorp at 0.28%

But if I use that link to do a calculation based on albumin, SHBG and total testosterone, it says I should have a free testosterone of 1.86%.

I'm confused by it. But what it seems like guys here are saying is that the direct measurement of free T is highly variable and therefore kind of unreliable...? So why should we even test for it? I don't know.
I have read Free T is what you feel. Maybe that is why we test for it or try to calculate or quantify it.
I have always wondered what Free T feels like?
Happier
Hornier
Stronger
Smeller
???

Sorry Kirk I am feeling frisky tonight I hope you don't mind the joking around?
 

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This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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