Kyzatrex - A New Oral T Option: Kyzatrex's pharmacokinetics and delivery system for effective use

madman

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Hayden Collier, PharmD is the director of clinical services at nuBioAge. He is committed to advancing healthcare through innovative, patient-centered approaches. With a passion for weightlifting, he draws parallels between the discipline of fitness and the importance of prevention in modern medicine. Hayden’s expertise extends beyond the pharmacy, blending sports science with cutting-edge medical strategies to redefine how we approach health and longevity. A dedicated husband, father, and sportsman, he brings the same focus and energy to both personal and professional life, always striving to inspire others to take charge of their well-being.

Dr. Collier joins us today to discuss innovative testosterone therapies, particularly focusing on Kyzatrex, a groundbreaking oral testosterone formulation. Hayden explains the unique delivery system of Kyzatrex, which bypasses first-pass metabolism to enhance safety and effectiveness, and how it challenges traditional testosterone therapy norms. He sheds light on the distinct differences in dosing and bioavailability between Kyzatrex and conventional therapies, offering new possibilities for preserving hormonal functions while delivering effective results. We also tackle the often-overlooked topic of testosterone replacement therapy (TRT) for women, discussing both its potential benefits and the obstacles it faces.




Topics discussed in this episode include:


* How Dr. Collier transitioned from retail pharmacy to functional and anti-aging medicine.

* How Kyzatrex offers safety benefits through a unique delivery system.

* Why Kyzatrex is changing perceptions with its short-acting ester and liver-friendly delivery system.

* How Kyzatrex's dosing and bioavailability advantages improve hormonal functions throughout the day.

* Why testosterone replacement therapy for women faces challenges and industry resistance.

* How studies on trans men provide insights into potential

* TRT benefits for women.

* Why Kyzatrex is only available through select pharmacies and not major chains.

* How nuBioAge enhances practitioner access and education regarding testosterone therapies.

* Using YDH Academy’s courses to advance functional medicine practice and education.

* Why it's important to understand Kyzatrex's pharmacokinetics and delivery system for effective use.

* How testosterone therapy's stigma affects patient willingness to seek out treatment.

* Why Kyzatrex may offer fewer side effects like erythrocytosis compared to traditional therapies.

* How patient consultation and informed decision-making are vital when considering off-label therapies.
 
 
Pros/Cons oral TU (51:24-57:12)

*one of the things that the orals have transformed is the concept that you have to have a continually high level of testosterone to get the benefits and clearly that's not true and the safety profile seems to be improved by having levels that fluctuate some during the day returning to close to or even baseline


 
 

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HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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