Is there any issue injecting in the same muscle every time?

Pacman

Active Member
I inject twice a week (Cyp on Mon/Tues -and- Prop on Fri/Sat), and I always inject in my right thigh muscle (quads). I don't feel any particular soreness or pain that I can complain about, so I am just wondering if there's any reason to alternate between the muscles I inject into? Or does it not matter at all?
 
I go left/right upper thigh. When I started I was caught up in the this notion of poking holes and needing to rotate four spots every time and then I stopped worrying and got on with it. For something you commit to for life, worrying about poking yourself is counterproductive, esp if using insulin size needles.
 
It's not the worry that stresses me out, it's the legitimate possibility that poking a sharp metal foreign object into the same muscle twice a week may do some long term damage. It barely hurts at all, and rarely leaves soreness anymore. I find it quite awkward to inject into any other muscle, but I will alternate if there is some real reason to do so.
 
It's not the worry that stresses me out, it's the legitimate possibility that poking a sharp metal foreign object into the same muscle twice a week may do some long term damage. It barely hurts at all, and rarely leaves soreness anymore. I find it quite awkward to inject into any other muscle, but I will alternate if there is some real reason to do so.

Maybe this isn't for you then. You know you can use a subcutaneous method with 29g, .5" syringe the same a dibetic uses, right? Your post infers you use some large gauge harpoon in to the muscle when there is clearly a better way.
 
Pacman- I think the main concern is that decades in, you may start to form scar tissue from the cumulative effect of the micro-trauma from injections.

One recommendation I've seen from Jay at Fab Fit Over 40 is to use Foam Rollers or Beastie Balls to break up some of that scar tissue that might form.

Another option is subcutaneous injections if that works for you, as that does not cause intramuscular scar tissue formation.

In some ways, we're in new territory here, as it's only recently that substantial numbers of guys have been on lifetime TRT spanning uninterrupted decades. So it's not clear what the long term effects will be. The precautionary principle would suggest to me that site rotation is probably prudent if it's convenient enough and not a hindrance to compliance.

Hope that helps.
 
It's not the worry that stresses me out, it's the legitimate possibility that poking a sharp metal foreign object into the same muscle twice a week may do some long term damage. It barely hurts at all, and rarely leaves soreness anymore. I find it quite awkward to inject into any other muscle, but I will alternate if there is some real reason to do so.

You can inject with a 27 gauge 1/2 inch syringe at 90 degrees into muscle (shoulders and legs) without scarring or local injection site reactions.
 

hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

Beyond Testosterone Podcast

Online statistics

Members online
2
Guests online
740
Total visitors
742

Latest posts

Back
Top