Is My e2 Too Low?

Brettski99

New Member
Here is latest batch of test results. Is my estridiol to low now? I have brain fog and feeling like Crap. Tired: fatigued.

TESTOSTERONE, TOTAL, MALES (ADULT), IATESTOSTE...
869
Low In Range High
250-827 ng/dL

In Range (4)
HEMATOCRIT
49.7
Low In Range High
38.5-50.0 %

HEMOGLOBIN
16.4
Low In Range High
13.2-17.1 g/dL

ESTRADIOL
18
In Range High
< OR = 39
Estradiol, Ultrasensitive, LCMSMS assay is recommended
(order code 30289).
PSA, TOTAL
0.7
In Range High
< OR = 4.0 ng/mL

Test is a little higher as I pulled more than I thought into syringe that day. Blood test done 24 hrs after injection.
 
Here is latest batch of test results. Is my estridiol to low now? I have brain fog and feeling like Crap. Tired: fatigued.

TESTOSTERONE, TOTAL, MALES (ADULT), IATESTOSTE...
869
Low In Range High
250-827 ng/dL

In Range (4)
HEMATOCRIT
49.7
Low In Range High
38.5-50.0 %

HEMOGLOBIN
16.4
Low In Range High
13.2-17.1 g/dL

ESTRADIOL
18
In Range High
< OR = 39
Estradiol, Ultrasensitive, LCMSMS assay is recommended
(order code 30289).
PSA, TOTAL
0.7
In Range High
< OR = 4.0 ng/mL

Test is a little higher as I pulled more than I thought into syringe that day. Blood test done 24 hrs after injection.

We're going to need much much more information than this for a productive conversation.

Protocol, the rest of the lab results, how long you've been on TRT, and age.

Vince is right, assuming you're not on every day injections, this is way too soon after injecting to have been tested. You should get labs done at day of injection but before injection. Anything else will result in less actionable information.

Another thing to keep in mind is that even your lab that you used(Quest probably) has stated you ordered the wrong estradiol test. You need the ultrasensitive in order for the test results to have any meaning.
 
Back in July you noted that the lab results indicated your estradiol was tested via the LC, MS/MS method (that is the correct test to use). Is the same notation on your most recent lab report?
 
Gents, thanks for the reply. This is the basic set of blood work the urologist tests. I have to ask for the estriadol as he doesn't test that, and i never checked to see that it was the sensitive test. Is there a standard list of markers we should be getting tested regularly? I am going in an a months time and want to be prepared so i can have a good starting point for assistance, or if he wont do the bloodwork i request i need to find someone else.
 
Gents, thanks for the reply. This is the basic set of blood work the urologist tests. I have to ask for the estriadol as he doesn't test that, and i never checked to see that it was the sensitive test. Is there a standard list of markers we should be getting tested regularly? I am going in an a months time and want to be prepared so i can have a good starting point for assistance, or if he wont do the bloodwork i request i need to find someone else.

Here is a basic overview on testing.

https://www.excelmale.com/forum/sho...e-and-During-Testosterone-Replacement-Therapy
 

hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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