Smokin Joe
Active Member
This is interesting and there are a few other articles out there relating to this.
I know it was a mouse model study but that's how things start.
What lead me to look into it is that I have had IDS and Digestive issues over the years.
I have always had low free T with normal Total T.
But when I started TRT some years back the IBS was minimal at most if any at all.
Recently I stopped TRT again (Natesto) due to sores in my nose. This was a trial for me and Natesto.
I was going to try a restart as I have been know to do over the years.
Anyway I've been off for about a month and I had a bad flare of IBS this week. Excruciating.
After reading some of the studies I decided to try 50mg Cypionate yesterday (Tuesday) August 29th.
Within a few hours my IBS settled down by about 2/3rds.
No meds involved...
Going to try 100mg a week again for a while to see what happens.
Will report.
In a hurry as we are in the path of the storm and the weather is getting rough in South Georgia....
I couldn't get to article to attached but copied the link of a study.
www.ncbi.nlm.nih.gov
I know it was a mouse model study but that's how things start.
What lead me to look into it is that I have had IDS and Digestive issues over the years.
I have always had low free T with normal Total T.
But when I started TRT some years back the IBS was minimal at most if any at all.
Recently I stopped TRT again (Natesto) due to sores in my nose. This was a trial for me and Natesto.
I was going to try a restart as I have been know to do over the years.
Anyway I've been off for about a month and I had a bad flare of IBS this week. Excruciating.
After reading some of the studies I decided to try 50mg Cypionate yesterday (Tuesday) August 29th.
Within a few hours my IBS settled down by about 2/3rds.
No meds involved...
Going to try 100mg a week again for a while to see what happens.
Will report.
In a hurry as we are in the path of the storm and the weather is getting rough in South Georgia....
I couldn't get to article to attached but copied the link of a study.
Diminished androgen levels are linked to irritable bowel syndrome and cause bowel dysfunction in mice - PMC
Functional gastrointestinal disorders (FGIDs) have prominent sex differences in incidence, symptoms, and treatment response that are not well understood. Androgens are steroid hormones present at much higher levels in males than females and could be ...
www.ncbi.nlm.nih.gov
