Inside the Brain: Scientists Debate Omega-3s, DHA vs EPA, and the Truth About Mental Health & Fats

madman

Super Moderator

In this podcast, I bring the three top scientists who know more about fats and the brain than any others - Professor Michael Crawford, visiting Professor at Imperial College London and head of the Institute of Brain Chemistry and Human Nutrition, Professor William Harris from the Fatty Acid Research Institute (FARI) and neuroscientist Dr Simon Dyall, a director of of the International Society for the Study of Fatty Acids and Lipids - to get inside our brains.

I’m most interested in the point of disagreement, the contradictions, the evidence that doesn’t fit the model. So often, by stirring things up we learn something new. Is it all about omega DHA? So why is evidence for EPA sometimes working even better for mental health? What about phospholipids? Is it all about choline, which is just one of five phospholipids. Where does vitamin D, a fat based hormone fit in? These are some of the topics we explore.
 

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

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The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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