Increased FT3 increases Pregnenolone => Coversion?

meanbreen

Member
I have seen Nelson cite selfhacked.com a few times so must be reputable...just read this:
Low T3 symptoms:
Low Pregnenolone and High LDL (R) – anxiety, bad moods, and low motivation are indicators of low pregnenolone. T3 thyroid hormones convert LDL to pregnenolone. Unless you take pregnenolone, you won't know what a deficiency feels like.
I thought all along that you should address adrenal issues before treating the thyroid, but this is actually saying that increasing T3 could help the conversion from cholesterol to Pregnenolone. I am just interested because my T3 is on the low side, high LDL, and low adrenal function (low DHEA, Prog, Preg)
Thoughts?

https://selfhacked.com/blog/check-thyroid-hormones-t3-low-without-blood-test/

 

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Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

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The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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