Mercury toxicity on Endocrine system and Hormones !!

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Mercury has been found to be an endocrine system disrupting chemical in animals and people, disrupting function of the pituitary gland, thyroid gland, parathyroid gland, thymus gland, adrenal gland, pineal gland, enzyme production processes, and affecting many hormonal and enzymatic functions at very low levels of exposure .

Thyroid conditions are extremely common and adversely affect the health of millions of people, though most cases are undiagnosed .


As will be seen, toxic metal exposures such as mercury can accumulate and block or inhibit any of these necessary processes, as can other factors. The hypothalamus also controls hormone secretions by the pituitary gland. Mercury has been found to commonly accumulate in the hypothalamus, affecting hormone secretions of the pituitary or thyroid gland and many bodily functions. Calcitonin is another hormone secreted by the thyroid gland that maintains blood calcium levels and prevents hypercalcemia and which can be affected.

Other common hormone problems are related to the adrenal glands. The adrenal medulla manufactures epinephrine and norepinephrine (adrenaline and noradrenaline) – the fight or flight hormones. Prolonged stress and anxiety commonly cause imbalances of these hormones, and also can be a factor in causing mercury to accumulate in the endocrine gland. Mercury tends to accumulate in body areas that are stressed or inflamed due to various factors.
The adrenal cortex makes steroid hormones (cortisone, hydrocortisone, testosterone, estrogen, DHEA, pregnenolone, aldosterone, androstenedrone, progesterone. Some of these are also made in other parts of the body. The hormone aldosterone, together with the kidneys, regulates the balance of sodium and potassium in the body, which is commonly out of balance. Mercury can accumulate in the adrenal gland and inhibit proper function of any of these hormones. Both mercury and stress commonly cause imbalances that result in adrenal fatigue, which is a factor in chronic fatigue.
Adrenal fatigue can be caused by chronic anxiety or stress, poor nutrition, toxic metal accumulation, etc. The adrenals can become depleted leading to fatigue, weakening of immune response, disrupted sugar metabolism, etc. Environmental toxic exposure such as mercury can block or inhibit any of the adrenal hormone processes and contribute to such conditions.

Dental amalgam fillings have been documented to be the largest source of mercury in most people who have several amalgam fillings, and most people with several amalgam fillings get daily exposure of mercury at levels well above U.S. government health guidelines which amount to about 4 to 8 micrograms per day. Mixed metals in the mouth such as amalgam dental fillings, metal crowns, and metal braces have been found to result in galvanic currents in the metals which drive the metals into the saliva and tissues of the oral cavity at high levels as well as systemically, with accumulations in the brain and hormonal glands.

Studies have documented that mercury causes hypothyroidism ,damage of thyroid RNA, autoimmune thyroiditis , and impairment of conversion of thyroid T4 hormone to the active T3 form.

Mercury (especially mercury vapor from dental amalgam or organic mercury) rapidly crosses the blood brain barrier and is stored preferentially in the pituitary gland, thyroid gland,hypothalamus, and occipital cortex in direct proportion to the number and extent of dental amalgam surfaces,and likewise rapidly crosses the placenta and accumulates in the fetus including the fetal brain and hormone glands at levels commonly higher than the level in the mother.

Mercury accumulates in the adrenal gland and disrupts adrenal gland function.
In general immune activation from toxics such as heavy metals resulting in cytokine release and abnormalities of the hypothalamus-pituitary-adrenal axis can cause changes in the brain, fatigue, and severe psychological symptoms such as depression, profound fatigue, muscoskeletal pain, sleep disturbances, gastrointestinal and neurological problems as are seen in CFS, Fibromyalgia, and autoimmune thyroiditis.

Mercury(and other toxic metals) has been found to accumulate in the pineal gland and reduce melatonin levels.

There is also evidence that mercury affects neurotransmitter levels which has effects on conditions like depression, mood disorders, ADHD, etc. There is evidence that mercury can block the dopamine-beta-hydroxylase (DBH) enzyme. DBH is used to make the noradrenaline neurotransmitter and low noradrenaline can cause fatigue and depression. Mercury molecules can block all copper catalyzed dithiolane oxidases, such as coproporphyrin oxidase and DBH.

Mercury has been found to cause hormonal changes which cause hair loss and greying of hair. In a large German study where 20,000 were tested, allergies and hair-loss were found to be 2-3 times as high in a group with large numbers of amalgam fillings compared to controls.

http://www.flcv.com/endohg.html
 
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