Hypogonadism in HIV Positive Men

Jinzang

Member
This is a review article discussing the treatment of hypogonadism in HIV positive men, with a discussion of several cases. The full text of the article is available online. The introduction says:

"Hypogonadism commonly affects HIV-positive men and is associated with a variety of clinical symptoms adversely affecting quality of life. However, symptoms of hypogonadism may be non-specific and attributed to a variety of causes, making the diagnosis challenging. An association between HIV infection and hypogonadism has long been recognised, particularly among those with advanced immunosuppression. Although the introduction of anti-retroviral therapy (ART) has lowered the incidence of hypogonadism among HIV infected men, it remains an issue, and interpretation of biochemical results and presentation is not straightforward. This article reviews the clinical features and diagnosis of hypogonadism in HIV-infected adult men, illustrated with a series of clinical case descriptions."
 

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Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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