HRT & Women: A Rational Medical Decision

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Hormone therapy for menopausal women is one of the best examples of precision medicine in clinical practice and remains the most effective first-line treatment for the common symptoms of menopause, according to Nanette Santoro, MD, professor and chair of reproductive endocrinology and infertility, department of obstetrics and gynecology at the University of Colorado Denver. Her remarks were delivered to the North American Menopause Society's annual meeting. The decisions of whether to initiate HT — and which formulation — are the embodiment of what precision medicine is all about, she said.

Contrast that attitude with the response so many men receive from their doctors when they approach them for help with a suspected case of hypogonadism.

"HT remains most effective first-line choice for menopausal symptoms," Healio, Endocrine Today, 13 October 2017

https://www.healio.com/endocrinolog...ive-first-line-choice-for-menopausal-symptoms
 

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TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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