How to Stop Antidepressants Safely

Nelson Vergel

Founder, ExcelMale.com
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"I'd originally gone on Zoloft [sertraline, a common antidepressant] in an effort to get off marijuana," recalls Ray, 43, a New York City public-relations professional diagnosed with HIV in 2004. But once Ray finally kicked pot, he decided to taper off the Zoloft over the course of six weeks -- and that's where things got unpleasant.

"At random moments throughout the day, it was like a bug zapper was going off in my brain," he recalls. "I'd be dizzy and disoriented. I told my doctor, and he said all that was normal, so I just put up with all of it because I wanted to get off Zoloft. But it wasn't fun."

Antidepressants Can Be Hard to Withdraw From. Here's How to Do It Right.
 

hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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