"How Do I Take Erectile Dysfunction Medication?

madman

Super Moderator

In this episode, urologists Dr. Justin Dubin and Dr. Kevin Chu tackle one of the most common questions surrounding men's sexual health - how to properly use medications like Viagra and Cialis for erectile dysfunction.

Many patients express frustration when these medications don't seem to work for them, but the doctors explain that the issue is often improper usage, not the medications themselves. They also discuss the common myths and misconceptions around these ED treatments, clarifying that they do not provide an "instant erection" as depicted in the media.

The conversation explores the nuances of taking these medications correctly - the importance of sexual arousal, timing the doses properly, and understanding the unique pharmacological profiles of Viagra versus Cialis. The doctors also address common concerns patients have, such as the risks of heart attacks, debunking these misconceptions.

This episode serves as a guide to optimize your use of ED medications and have more productive conversations with healthcare providers. Whether you're considering trying these treatments or have struggled to make them work, this offers valuable insights that can transform your sexual health. Tune in now on Spotify, Apple Podcasts, Amazon, and YouTube.
 
Pay close attention!


Tachyphylaxis (22:05-23:27)
Definition: Tachyphylaxis is the appearance of progressive decrease in response to a given dose after repetitive administration of a pharmacologically or physiologically active substance.
 
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*These drugs are generally very safe and have no impact on the body and they do not develop any resistance

*Over time these drugs will not work, not because of the resistance but because our body gets older and our vessels, especially penile arteries get weaker as we get older
 
Hitting the nail on the f**KING head!

*Over time these drugs will not work, not because of the resistance but because our body gets older and our vessels, especially penile arteries get weaker as we get older
 

75% of patients start with pills as a first line therapy

*but about 50% actually discontinue due to medication failure no longer achieving the SAME RESPONSE as BEFORE and interestingly that doesn't seem to be a TOLERANCE but rather just the AGING PROCESS and the MALE BODY CONTINUES TO GET WORSE OVER TIME
 

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

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The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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