How do I calculate “free estradiol”?

Gunga

Member
Do I need to just purchase the lab? If there is one?

I feel good but I’m trying to determine where I fall within these ranges.

My SHBG is 15.6

My Estradiol Sensitive is 16.5

Thanks Gents!
 
There is a test and there is a calculator. See discussion here:
The calculated values seem to line up pretty well with the tests for some guys. You do need to measure testosterone and SHBG in addition to estradiol. Ideally albumin too. The calculation seems to work better with the standard estradiol test. But this probably requires that you don't have elevated CRP to throw off the test.
 
There is a test and there is a calculator. See discussion here:
The calculated values seem to line up pretty well with the tests for some guys. You do need to measure testosterone and SHBG in addition to estradiol. Ideally albumin too. The calculation seems to work better with the standard estradiol test. But this probably requires that you don't have elevated CRP to throw off the test.
Thank you Cataceous! The response is much appreciated.
 

hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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