How BMI Influences Testosterone Boosts: Up-Titration Results for Oral Testosterone Undecanoate

[madman]

 

[madman]

Thread 'Optimizing T Therapy: Results of Predictable Up-Titration of Oral TU (Jatenzo)'

Apr 11, 2025

As always bringing you the latest and greatest.....Nelson's house is where it's at!

Leaving everyone in the dust here!

Time to purge!




* These results suggest it may be beneficial to start men at a higher starting dose of TU than the approved dosing regimen to minimize multiple time-intensive dose titrations and allow patients to reach therapeutic T levels in a more timely manner. Future studies should aim to evaluate patient-specific variables to determine which patients would benefit from starting at higher TU doses initially to guide clinician management of...

• madman
• hypogonadism; oral-t; titration; t-therapy
• Replies: 4
• Forum: Testosterone and Men's Health Articles

 

[Cataceous]

Apparently this study did not track free testosterone, which makes the results considerably less useful. Higher BMI is expected to correlate with lower SHBG [R], which leads to lower total testosterone for the same level of free testosterone. Therefore these cohorts with different BMIs could have the same level of free testosterone and not even need the dose titration.