High Free T Has Doctor Worried

MR. evil

New Member
Just had my regular 6 month follow up with my endo. I'm currently taking 125mg test cyp via weekly IM injections. My total T was a little on the high side but my doctor wasn't really concearned with that. But he wasnt happy with my Free T number and wants me to lower my dose to 100mg. For a couple of months and see if here is any change.

Total T. 830
Free T. 25
PSA. 1.2

I wished I had asked my doctor, but what is the downside to a high level of free T?
 
Will you post the reference ranges for each test? Determining free testosterone values is frequently a major headache for patient and doctor. Was your free testosterone result derived via a direct or calculated process? What was your estradiol? Finally, most importantly, how are you feeling?
 
You're a little over 3%, which reflects your SHBG is on the low end; possibly albumin as well. That's pretty close to where I am at as well, many here actually in that ballpark. So, regardless of your total test, you can figure multiplying it by 3, and that will get you relatively close (830 x 3% = 24.9). I'd still run all the labs, but it gives you a perspective if in the event you only have a total testosterone lab to work with ...

IMO, that's not really that high all things considered ... I personally do best in the 18 -22 range or so, but again it's an individual thing. Maybe your doctor is treating the number more than the patient if he's focused on that aspect without checking-in on your overall well being? When did you run labs in relation to your injection schedule?

If you're not having any sides, and you feel great, there really isn't a severe downside!! On the flip side, 125mg down to 100mg isn't significant either, and maybe tweaking it a bit provides a better overall program? I know in my 8 years of treatment, I have seen 80mg/wk up to 200mg/week ... Taken 1x, 2x and even 3x ... SubQ and IM. 60mg x 2/wk tends to work for me (sometimes even a little less), plus 250iu x 2 of HCG.

Whatever route you go, I'd suggest at least splitting it up 2x per week.
 

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TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

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Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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