Hello forum, glad to be here.

Outcome

Active Member
I look forward to exchanging ideas and discussion topics with all of you. Please excuse me in advance if I seem blunt or terse at times, or make spelling mistakes. I've learned a lot here already just lurking around but this forum helped decide to use Defy medical and I'm glad I did. I just got started with them and got my meds this week. But I've been on trt since Sept of 16 with a 2 month of break May and June. Did my first self injection this past Monday the 10th, much easier than I thought but it still took me a long time to get it all done. I tend to over analyze things. I did my consultation with Dr. Calkins, very thorough and knowledgeable. Looking forward to discussing things with all of you. Have a great day.
 
Welcome , a lot of knowledgeable and helpful people here.. Best of all , we all can relate to each other in one way or another.. I'll be starting my journey with Defy next month myself . Look forward to seeing your progress...

What are your symptoms if you don't mind me asking?
 
Thanks Vince, Antcon
No problem. My symptoms. Fatigue, brain fog, lack of motivation, some muscle mass reduction. They all started coming back on me may and June. Glad to be back on a program. I moved to a rural area for a new job and driving for weekly injections wasn't going to cut it. Plus I lost my insurance. Then I found Defy. I guess I should mention some stats: 48. 170 lbs. Reasonably healthy but a challenge with blood pressure now. Taking amlodipine. Before I stopped in May I was getting a 200 mg dose weekly that got me to around 1150 and free 25 but estradiol climbed along with hematocrit. I donated blood back in February that got my hematocrit to 49ish and in May it was 51 . So I may donate again. One other problem with my prior program was the lack of support for rising estrogen. Looking back I really needed an ai but they wouldn't prescribe one. I was in the dark about hcg but now I inject that too. So, the Defy program seems to cover all the bases and they are there to help you if something isn't right. My current program is: 140 mg test - 800 iu hcg - .25 mg anastrozole all weekly but split into 2 Injections. Dhea 25mg every night. Thanks for the forum. Its very informative.
 
Thanks Vince, Antcon
No problem. My symptoms. Fatigue, brain fog, lack of motivation, some muscle mass reduction. They all started coming back on me may and June. Glad to be back on a program. I moved to a rural area for a new job and driving for weekly injections wasn't going to cut it. Plus I lost my insurance. Then I found Defy. I guess I should mention some stats: 48. 170 lbs. Reasonably healthy but a challenge with blood pressure now. Taking amlodipine. Before I stopped in May I was getting a 200 mg dose weekly that got me to around 1150 and free 25 but estradiol climbed along with hematocrit. I donated blood back in February that got my hematocrit to 49ish and in May it was 51 . So I may donate again. One other problem with my prior program was the lack of support for rising estrogen. Looking back I really needed an ai but they wouldn't prescribe one. I was in the dark about hcg but now I inject that too. So, the Defy program seems to cover all the bases and they are there to help you if something isn't right. My current program is: 140 mg test - 800 iu hcg - .25 mg anastrozole all weekly but split into 2 Injections. Dhea 25mg every night. Thanks for the forum. Its very informative.

Nice , glad you got things going on the right track.. I too have fatigue, almost dibilitating at times. Have you noticed improvement in your fatigue?
 
Hey Felinemedi how are you? I hope the time you spend here is fun and educational. I've learned a lot here in a short time.
 

hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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