Hard Flaccid Syndrome (HFS)

madman

Super Moderator
* Typical age: 20-40, often post-genitourinary trauma, with underlying anxiety and/or depression








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Key Message
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* Typical age: 20-40, often post-genitourinary trauma, with underlying anxiety and/or depression




What is Hard Flaccid Syndrome?

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* when we talk about the pathophysiology you have to understand they're all theories/hypothesis from case reports, case series, some review articles which is still ongoing and still changing


Pathophusioogy
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* Treatment options. available are either limited or demonstrate mixed efficacy results




Treatment options

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Physical Therapy
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Medications
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Other Therapies
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Management Challenges
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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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