madman
Super Moderator
In this episode of You Are Not Broken, Dr. Kelly Casperson sits down with endocrinologist and obesity medicine expert Dr. Rocio Salas-Whalen for a deep dive into GLP-1 medications (like Ozempic, Wegovy, and Mounjaro).
They cover everything you should be asking but probably haven’t heard:
- The real reason GLP-1s exploded post-COVID
- How these medications actually work (hint: it’s not just about appetite)
- Why preserving muscle mass is non-negotiable—and how to do it
- Hormones + GLP-1s: what the latest data says
- Microdosing, maintenance, and the future of these meds
- The emotional and social impact of weight loss no one talks about
- And the biggest misconceptions about safety, cost, and who should prescribe them
Whether you're considering starting a GLP-1, currently using one, or just trying to untangle the noise, this conversation is packed with clarity, compassion, and actionable advice.
Chapters
00:00 Introduction to GLP-1 Medications
02:59 The Impact of COVID-19 on Obesity Awareness
05:54 Understanding GLP-1: History and Mechanism
09:10 The Role of GLP-1 in Weight Loss and Muscle Preservation
12:05 Nutrition and Muscle Mass: The Importance of Protein
15:06 The Gender Disparity in Hormone Treatments
17:57 Endocrinology and the Treatment of Sex Hormones
21:02 Personalization in GLP-1 Dosing
23:44 Understanding GLP-1 and Body Composition
27:12 Cost and Accessibility of GLP-1 Medications
28:38 Mechanism of Action of GLP-1
30:43 Impact of GLP-1 on Lifestyle and Relationships
33:57 Misconceptions and Safety of GLP-1 Medications
36:22 Education and Resources for Practitioners
37:25 Future of GLP-1 Drug Development
38:59 Metabolic Markers and Women's Health
41:25 Rocio's Upcoming Book and Patient Care Insights
46:06 Final Thoughts on GLP-1 and Patient Relationships