Genetic Testing For Prostate Cancer



0:22 What is the difference between a "genetic" and a "genomic" test?
1:12 How important is genetic or genomic testing to the average prostate cancer patient?
3:31 Do 5% of people have a BRCA mutation?
3:42 Should all prostate cancer patients test to see if they have a BRCA mutation?
5:09 What are "somatic" and "germline" testing?
5:56 What tests are most often used to check for BRCA mutation, and when?
7:40 Why is that patients on active surveillance are so unlikely to die from prostate cancer?
8:21 In what other contexts are genetic tests useful for prostate cancer patients?
10:14 What are the usual next steps after a patient gets their genetic test results?
10:45 How can patients best understand the results of their genetic test?
12:19 Are genetic tests usually covered by insurance and Medicare?
12:34 Is it a matter of all men should be tested?
14:01 How impactful are genetic tests on the average patient's treatment plan?
15:08 Alex's conclusions
16:39 If you need more information
 
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⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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