Free T too high

DirtyDusty

New Member
If my TT is 680 Ng/dL and free T is 208 pg/ml, am I too high? I read that there was an ideal ratio, but how is it calculated? My SHGB has dropped from 22 to 16 since my last lab, 6 weeks ago.
 
That’s what I was wondering. I couldn’t remember exactly what the ratio deal was, just that I had read a while back about some ratio that was ideal. I had TT/FT confused with TT/E2.

Are you saying that the TT/E2 is garbage?
I will jump in and amswer for my friend @Vince Carter. Don't invest time in the ratio (other than as one data pointout of many). It is an attempt to make some sense out of the somewhat bewildering flow of ideas on estradiol levels. It can not be used in isolation.
 
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Your free T is a calculated value, so you can compare it to that of anyone who has accurate measurements for SHBG and total testosterone. This is in contrast to measured free T, where labs can have entirely different ranges.

For example, my TT has been around 800 ng/dL, and SHBG around 30 nmol/L, so my free T is pretty close to yours. This level is getting to be high normal for a young guy. Guys on TRT are regularly going well above this, at least 25-30 ng/dL, and don't seem to run into problems. But it's still an individual thing, and you may need to experiment if you feel there's room for improvement. This is anecdotal, but my informal survey of guys visiting PeakTestosterone.com with symptoms of low T says that they most often have free T around or under 10 ng/dL (100 pg/dL).
 

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TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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