Hey guys,
Looking for a quick sanity check on my current numbers and T:E2 ratio.
I spent the first part of the year dialing in my dose and settled on my current protocol of ~218 mg/wk of Test Cypionate (pinned 62.5 mg EOD) on February 24th.
On my previous labs from late January (while I was still adjusting), my Total T was around 1475 ng/dL and my E2 had crept up to ~54 pg/mL (200 pmol/L). My sleep was at the time was fragmented, I was bloated and I felt anxious at work, all of which I figured was due to high E2.
To get the E2 under control, I introduced Anastrozole at 0.25 mg EOD. Since making that change, my sleep has improved significantly and I have zero joint issues. However, I'm just not feeling the positive benefits (drive, confidence, energy) I was expecting to experience with my Testosterone sitting at these elevated levels.
Here is my latest bloodwork on the AI (drawn March 3rd):
I'm running these enhanced levels as a saturation strategy for 12 weeks due to likely having had low levels for years prior to starting TRT.
I'm aware of the risks of running these levels and will get full blood work done frequently.
Appreciate the feedback!
Looking for a quick sanity check on my current numbers and T:E2 ratio.
I spent the first part of the year dialing in my dose and settled on my current protocol of ~218 mg/wk of Test Cypionate (pinned 62.5 mg EOD) on February 24th.
On my previous labs from late January (while I was still adjusting), my Total T was around 1475 ng/dL and my E2 had crept up to ~54 pg/mL (200 pmol/L). My sleep was at the time was fragmented, I was bloated and I felt anxious at work, all of which I figured was due to high E2.
To get the E2 under control, I introduced Anastrozole at 0.25 mg EOD. Since making that change, my sleep has improved significantly and I have zero joint issues. However, I'm just not feeling the positive benefits (drive, confidence, energy) I was expecting to experience with my Testosterone sitting at these elevated levels.
Here is my latest bloodwork on the AI (drawn March 3rd):
- Total T: 1552 ng/dL
- E2 (Oestradiol): 32.4 pg/mL (119 pmol/L)
- SHBG: 31 nmol/L
- Calculated T:E2 Ratio: ~48
- What are your thoughts on a T:E2 ratio around 48 at these androgen levels?
- With Total T pushing 1550+, is keeping E2 tightly controlled at ~32 pg/mL generally the sweet spot, or could the lack of expected "high T" benefits be directly related to having such a high ratio? Do guys running enhanced levels prefer letting E2 run a bit higher to balance things out?
I'm running these enhanced levels as a saturation strategy for 12 weeks due to likely having had low levels for years prior to starting TRT.
I'm aware of the risks of running these levels and will get full blood work done frequently.
Appreciate the feedback!
