Favipiravir: positive effect for mild to moderate cases of COVID-19

sammmy

Well-Known Member
Glenmark’s phase III favipiravir study finds drug speeds clinical improvement for some patients

Favipiravir COVID-19 studies summary:
Chinese clinical trials showed favipiravir to be ‘clearly effective’ – patients tested negative for the virus in an average of just four days, compared to 11 days for controls. Symptoms improved alongside reduced viral load, with lung function improving in 91% of patients on the drug, vs 62% of those without. In a Russian trial, body temperature in 68% of patients on favipiravir returned to normal in half the time of those in the control group. A trial in Japan, however, showed limited effect in people with higher viral load, suggesting it’s most likely to be of use in mild to moderate cases. Trials are also underway worldwide exploring the efficacy of favipiravir alone and in tandem with other drugs.
 
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TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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